ArticleSchizophrenia research2009
Polymorphisms in SLC6A4, PAH, GABRB3, and MAOB and modification of psychotic disorder features.
Article in Schizophrenia research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- A study of molecular changes relating to energy metabolism and cellular stress in people with Huntington's disease: looking for biomarkers.Journal of bioenergetics and biomembranes · 2013Trial
- Glial-neuronal crosstalk via GABA signaling: mechanistic insights into neuropsychiatric and neurological pathophysiology.Molecular psychiatry · 2026Review
- Blood‑brain barrier dysfunction in schizophrenia: Mechanisms and implications (Review).International journal of molecular medicine · 2025Review
- ASCL1 Is Involved in the Pathogenesis of Schizophrenia by Regulation of Genes Related to Cell Proliferation, Neuronal Signature Formation, and Neuroplasticity.International journal of molecular sciences · 2023Article
- Psychiatric polygenic risk as a predictor of COVID-19 risk and severity: insight into the genetic overlap between schizophrenia and COVID-19.Translational psychiatry · 2023Article
- Single-nucleotide Polymorphism of CTLA-4 (rs5742909) in Correlation with Schizophrenia Risk Factor.Journal of pharmacy & bioallied sciences · 2019Article
- The Sex Chromosome Hypothesis of Schizophrenia: Alive, Dead, or Forgotten? A Commentary and Review.Molecular neuropsychiatry · 2018Article
- Sex chromosome abnormalities and psychiatric diseases.Oncotarget · 2017Review
- Parsing psychosis subtypes through investigations of rare genetic variants.EBioMedicine · 2016Article
- Revisiting schizophrenia linkage data in the NIMH Repository: reanalysis of regularized data across multiple studies.The American journal of psychiatry · 2014Article
- Gene-sex interactions in schizophrenia: focus on dopamine neurotransmission.Frontiers in behavioral neuroscience · 2014Review
- Expression of GABAA α2-, β1- and ε-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder.Translational psychiatry · 2013Article
- Autonomous vascular networks synchronize GABA neuron migration in the embryonic forebrain.Nature communications · 2013Article
- A genome-wide quantitative linkage scan of niacin skin flush response in families with schizophrenia.Schizophrenia bulletin · 2013Article
- Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.Molecular psychiatry · 2012Article
- 13C-phenylalanine breath test detects altered phenylalanine kinetics in schizophrenia patients.Translational psychiatry · 2012Article
- Monoamine oxidase a and B gene polymorphisms and negative and positive symptoms in schizophrenia.ISRN psychiatry · 2012Article
- Sex-specific rates of transmission of psychosis in the New England high-risk family study.Schizophrenia research · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
We tested four genes [phenylalanine hydroxylase (PAH), the serotonin transporter (SLC6A4), monoamine oxidase B (MAOB), and the gamma-aminobutyric acid A receptor beta-3 subunit (GABRB3)] for their impact on five schizophrenia symptom factors: delusions, hallucinations, mania, depression, and negative symptoms. In a 90 family subset of the Irish Study of High Density Schizophrenia Families, the PAH 232 bp microsatellite allele demonstrated significant association with the delusions factor using both QTDT (F=8.0, p=.031) and QPDTPHASE (chi-square=12.54, p=.028). Also, a significant association between the GABRB3 191 bp allele and the hallucinations factor was detected using QPDTPHASE (chi-square=15.51, p=.030), but not QTDT (chi-square=2.07, p=.560).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.