ArticleArchives of oral biology2009
Small molecular weight proteins/peptides present in the in vivo formed human acquired enamel pellicle.
Article in Archives of oral biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 95 citations in OpenAlex.
- Quantitative proteomic analysis of the effect of fluoride on the acquired enamel pellicle.PloS one · 2012Trial
- Evidence of intact histatins in the in vivo acquired enamel pellicle.Journal of dental research · 2010Trial
- Article
- Exploring the Healing Powers of Histatins: From Oral Health to Therapeutics.International journal of molecular sciences · 2025Review
- Reducing Functional Domain of Histatin 5 Improves Antifungal Activity and Prevents Proteolytic Degradation.Microorganisms · 2025Article
- Positive Role of Saliva in the Oral Microbiome.Advances in experimental medicine and biology · 2025Review
- The Effect of a Nature-Based Gel on Gingival Inflammation and the Proteomic Profile of Crevicular Fluid: A Randomized Clinical Trial.Gels (Basel, Switzerland) · 2024Article
- Acquired enamel pellicle and biofilm engineering with a combination of acid-resistant proteins (CaneCPI-5, StN15, and Hemoglobin) for enhanced protection against dental caries - in vivo and in vitro investigations.Clinical oral investigations · 2024Article
- Accurate informatic modeling of tooth enamel pellicle interactions by training substitution matrices with Mat4Pep.Frontiers in materials · 2024Article
- Mechanistic Insights into Bioengineered Antibiofilm Enamel Pellicles.Journal of dental research · 2023Article
- Protease-inhibitors added to saliva in vitro influence the erosion protective effect of enamel pellicles.Scientific reports · 2023Article
- Novel bacterial proteolytic and metabolic activity associated with dental erosion-induced oral dysbiosis.Microbiome · 2023Article
- Article
- Engineered Salivary Peptides Reduce Enamel Demineralization Provoked by CariogenicMicroorganisms · 2022Article
- Novel impacts of saliva with regard to oral health.The Journal of prosthetic dentistry · 2022Review
- Modulation ofMicroorganisms · 2022Article
- Bioinspired caries preventive strategy via customizable pellicles of saliva-derived protein/peptide constructs.Scientific reports · 2021Article
- Analysing Complex Oral Protein Samples: Complete Workflow and Case Analysis of Salivary Pellicles.Journal of clinical medicine · 2021Review
- The salivary pellicle on dental biomaterials.Colloids and surfaces. B, Biointerfaces · 2021Review
- Salivary proteomic profile of dogs with and without dental calculus.BMC veterinary research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe aim of this study was to investigate the type and the nature of peptides present in the in vivo formed human acquired enamel pellicle.
designPellicle material was collected from 10 volunteers and subjected to sample preparations consisting of centrifugal filtration using a 10 kDa molecular weight cut-off membrane and high-resolution gel filtration chromatography. The fractions containing peptides <10 kDa obtained by both methods were analyzed by LC-ESI-MS/MS.
results78 natural pellicle peptides with molecular weights ranging from 766.9 Da to 3981.4 Da were identified originating from 29 different proteins.
conclusionsThe number of peptides present in acquired enamel pellicle appears to be large and this is likely to enhance the functional spectrum of this protein film. The presence of small peptides in pellicle may be functionally important since structure/function studies of many salivary proteins have shown that specific domains within these native proteins retain or even exhibit enhanced biological activities. The data present the basis for determining the precise function of these pellicle peptides and for gaining insights into the role pellicle plays in the oral cavity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.