Evidence map›Paper›PMID 19267228›Full record

ReviewJournal of neuro-oncology2009

Clinicopathologic features of recurrent dysembryoplastic neuroepithelial tumor and rare malignant transformation: a report of 5 cases and review of the literature.

Wilson Z Ray, Spiros L Blackburn, Sandro Casavilca-Zambrano, Carlos Barrionuevo, Jose E Orrego, Hugo Heinicke, Joshua L Dowling, Arie Perry

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Seizures in children with dysembryoplastic neuroepithelial tumors of the brain--A review of surgical outcomes across several studies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015
    Pooled it
  2. Article
  3. Other Less Prevalent Tumors of the Central Nervous System.Advances in experimental medicine and biology · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Awake surgery for hemispheric low-grade gliomas: oncological, functional and methodological differences between pediatric and adult populations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016
    Review
  11. Glioneuronal tumors of cerebral hemisphere in children: correlation of surgical resection with seizure outcomes and tumor recurrences.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016
    Article
  12. Article
  13. Epilepsy associated tumors: Review article.World journal of clinical cases · 2014
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Long-term epilepsy-associated tumors.Brain pathology (Zurich, Switzerland) · 2012
    Review
  19. A rare case of dysembryoplastic neuroepithelial tumor.Journal of clinical imaging science · 2012
    Article
  20. Intraventricular dysembryoplastic neuroepithelial tumor in a pediatric patient: is it the most common extracortical location for DNT?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wilson Z RayDepartment of Neurological Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8057, St. Louis, MO 63110, USA. rayz@nsurg.wustl.edu
Spiros L Blackburn
Sandro Casavilca-Zambrano
Carlos Barrionuevo
Jose E Orrego
Hugo Heinicke
Joshua L Dowling
Arie Perry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysembryoplastic neuroepithelial tumors (DNETs) have traditionally been viewed as benign "quasihamartomatous" tumors widely considered curable with surgery alone. More recently, case reports have described malignant gliomas arising after irradiation and recurrences following subtotal or even gross total resection. Herein, we describe five cases of DNET with recurrences 2-7 years after resection. Although the radiology was often alarming (e.g., new ring enhancing mass), the pathology remained benign in most cases. Nonetheless, a probably radiation induced anaplastic astrocytoma was encountered in one case 7 years after therapy. These findings suggest that these patients may need closer follow-up than initially suggested, lending further support to the notion that this tumor behaves more like a benign neoplasm, rather than a dysplastic or hamartomatous lesion.

Indexed as

AdolescentAdultBrain NeoplasmsCell Transformation, NeoplasticChildFemaleHumansMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalNeoplasms, NeuroepithelialYoung Adult

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.