ArticleThe Journal of general virology2009
Validation of high rates of nucleotide substitution in geminiviruses: phylogenetic evidence from East African cassava mosaic viruses.
Article in The Journal of general virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
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Who cites it
83 citing papers in PubMed.
- Into the wild: a long-term study of begomovirus community dynamics in a natural landscape.The Journal of general virology · 2026Article
- Viral and Host Factors Involved in Host Gain and Host Loss by Tomato Leaf Curl Begomoviruses in Tomato and Cucumbers.Molecular plant pathology · 2026Article
- Evolutionary origin and demographic trajectory of tomato spotted wilt virus (Orthotospovirus tomatomaculae).Archives of virology · 2026Article
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- SEGS-1 episomes generated during cassava mosaic disease enhance disease severity.Frontiers in plant science · 2024Article
- High-throughput sequencing discovered diverse monopartite and bipartite begomoviruses infecting cucumbers in Saudi Arabia.Frontiers in plant science · 2024Article
- Genetic Diversity, Evolutionary Dynamics, and Ongoing Spread of Pedilanthus Leaf Curl Virus.Viruses · 2023Article
- Amesuviridae: a new family of plant-infecting viruses in the phylum Cressdnaviricota, realm Monodnaviria.Archives of virology · 2023Article
- A shift of vector specificity acquired by a begomovirus through natural homologous recombination.Molecular plant pathology · 2023Article
- Sentinel plot surveillance of cotton leaf curl disease in Pakistan- a case study at the cultivated cotton-wild host plant interface.Virus research · 2023Article
- An Insight into Emerging Begomoviruses and their Satellite Complex causing Papaya Leaf Curl Disease.Current genomics · 2023Review
- Molecular Characterization of Three Apple Geminivirus Isolates in Crabapples Detected in Inner Mongolia, China.Plants (Basel, Switzerland) · 2023Article
- Cassava begomovirus species diversity changes during plant vegetative cycles.Frontiers in microbiology · 2023Article
- SEGS-1 a cassava genomic sequence increases the severity of African cassava mosaic virus infection inFrontiers in plant science · 2023Article
- Phylostems: a new graphical tool to investigate temporal signal of heterochronous sequences datasets.Bioinformatics advances · 2023Article
- Identification and characterization of a new geminivirus from soybean plants and determination of V2 as a pathogenicity factor and silencing suppressor.BMC plant biology · 2022Article
- Phylodynamics and Coat Protein Analysis of Babaco Mosaic Virus in Ecuador.Plants (Basel, Switzerland) · 2022Article
- Role of Diversity and Recombination in the Emergence of Chilli Leaf Curl Virus.Pathogens (Basel, Switzerland) · 2022Article
- Chilli leaf curl disease populations in India are highly recombinant, and rapidly segregated.3 Biotech · 2022Article
23 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
Whitefly-transmitted geminiviruses are major pathogens of the important crop cassava in Africa. The intensive sampling and sequencing of cassava mosaic disease-causing viruses that occurred in the wake of a severe outbreak in Central Africa (1997-2002) allowed us to estimate the rate of evolution of this virus. East African cassava mosaic virus and related species are obligately bipartite (DNA-A and DNA-B segments), and these two genome segments have different evolutionary histories. Despite these phylogenetic differences, we inferred high rates of nucleotide substitution in both segments: mean rates of 1.60x10(-3) and 1.33x10(-4) substitutions site(-1) year(-1) for DNA-A and DNA-B, respectively. While similarly high substitution rates were found in datasets free of detectable recombination, only that estimated for the coat protein gene (AV1), for which an additional DNA-A sequence isolated in 1995 was available, was statistically robust. These high substitution rates also confirm that those previously estimated for the monopartite tomato yellow leaf curl virus (TYLCV) are representative of multiple begomoviruses. We also validated our rate estimates by comparing them with those depicting the emergence of TYLCV in North America. These results further support the notion that geminiviruses evolve as rapidly as many RNA viruses.
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