ArticleEuropean journal of applied physiology2009
Muscle damage responses of the elbow flexors to four maximal eccentric exercise bouts performed every 4 weeks.
Article in European journal of applied physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02918682 (The Effects of a Multi-component Intervention on the Functional Capacity, Upper and Lower-body Muscle Strength, Balance and Gait in Frail Community-dwelling Older People), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of a Multi-component Intervention on the Functional Capacity, Upper and Lower-body Muscle Strength, Balance and Gait in Frail Community-dwelling Older People: a Randomized Clinical Trial
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Minimal Evidence for a Secondary Loss of Strength After an Acute Muscle Injury: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2017Pooled it
- Effects of Eccentric Exercise of the Extensors on Eccentric Exercise-Induced Muscle Damage of the Flexors in Limbs.Medicine and science in sports and exercise · 2025Trial
- Effect of Daily OralNutrients · 2021Trial
- Comparison in eccentric exercise-induced muscle damage among four limb muscles.European journal of applied physiology · 2011Trial
- Beyond the first bout: Adaptations to repeated injuries across physiological and pathological conditions.Physiological reports · 2026Review
- Muscle soreness but not neuromuscular fatigue responses following downhill running differ according to the number of exercise bouts.European journal of sport science · 2025Article
- Skeletal muscle adaptations following eccentric contractions are not mediated by keratin 18.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- The addition of blood flow restriction during resistance exercise does not increase prolonged low-frequency force depression.Experimental physiology · 2024Article
- Recovery markers in elite climbers after the national boulder climbing championship.Frontiers in sports and active living · 2024Article
- Adaptability to eccentric exercise training is diminished with age in female mice.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Influence of Cluster Sets on Mechanical and Perceptual Variables in Adolescent Athletes.International journal of environmental research and public health · 2023Article
- Training Load and Current Soreness Predict Future Delayed Onset Muscle Soreness in Collegiate Female Soccer Athletes.International journal of sports physical therapy · 2023Article
- Blood Flow Restriction Attenuates Muscle Damage in Resistance Exercise Performed Until Concentric Muscle Failure.International journal of exercise science · 2023Article
- Eccentric exercise per se does not affect muscle damage biomarkers: early and late phase adaptations.European journal of applied physiology · 2021Article
- Effect of Large Versus Small Range of Motion in the Various Intensities of Eccentric Exercise-Induced Muscle Pain and Strength.International journal of exercise science · 2021Article
- Exercise induced changes in echo intensity within the muscle: a brief review.Journal of ultrasound · 2020Review
- Changes in Urinary Titin N-terminal Fragment Concentration after Concentric and Eccentric Exercise.Journal of sports science & medicine · 2020Article
- Fast-Velocity Eccentric Cycling Exercise Causes Greater Muscle Damage Than Slow Eccentric Cycling.Frontiers in physiology · 2020Article
- Resistance training in young men induces muscle transcriptome-wide changes associated with muscle structure and metabolism refining the response to exercise-induced stress.European journal of applied physiology · 2018Article
- Contralateral repeated bout effect after eccentric exercise on muscular activation.European journal of applied physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since little is known about the repeated bout effect of more than two eccentric exercise bouts, this study compared muscle damage responses among four exercise bouts. Fifteen young (21.8 +/- 1.9 years) men performed four bouts of 30 maximal isokinetic eccentric contractions of the elbow flexors every 4 weeks. Maximal voluntary elbow flexion isometric and concentric strength, range of motion at the elbow joint (ROM), upper arm circumference, blood markers of muscle damage, and muscle soreness were measured before and up to 120 h following each bout. Changes in all measures following the second to fourth bouts were significantly (P < 0.05) smaller than those after the first bout. The decreases in strength and ROM immediately after the fourth bout were significantly (P < 0.05) smaller than other bouts. It is concluded that the first bout confers the greatest adaptation, but further adaptation is induced when the exercise is repeated more than three times.
Indexed as
Identifiers
19263073What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.