ReviewCell adhesion & migration
Modeling cell migration in 3D: Status and challenges.
Review in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Bridging hemodynamics, tissue mechanics, and pathophysiology in coronary artery disease: A new agent-based model with tetrahedral mesh integration.Journal of biomechanics · 2025Article
- Quantification of cell migration: metrics selection to model application.Frontiers in cell and developmental biology · 2023Review
- A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling.iScience · 2021Article
- Digitally Fabricated and Naturally Augmented In Vitro Tissues.Advanced healthcare materials · 2021Review
- Multivalent Binding of a Ligand-Coated Particle: Role of Shape, Size, and Ligand Heterogeneity.Biophysical journal · 2018Article
- Nischarin regulates focal adhesion and Invadopodia formation in breast cancer cells.Molecular cancer · 2018Article
- Integration ofFrontiers in physiology · 2018Article
- A stochastic algorithm for accurately predicting path persistence of cells migrating in 3D matrix environments.PloS one · 2018Article
- Computational model of mesenchymal migration in 3D under chemotaxis.Computer methods in biomechanics and biomedical engineering · 2017Article
- Comparison of cell migration mechanical strategies in three-dimensional matrices: a computational study.Interface focus · 2016Article
- A mathematical model of collective cell migration in a three-dimensional, heterogeneous environment.PloS one · 2015Article
- Integrative analysis of cancer imaging readouts by networks.Molecular oncology · 2015Review
- Probabilistic Voxel-Fe model for single cell motility in 3D.In silico cell and tissue science · 2014Article
- Modeling persistence in mesenchymal cell motility using explicit fibers.Langmuir : the ACS journal of surfaces and colloids · 2014Article
- Influence of the microenvironment on cell fate determination and migration.Physiological genomics · 2014Review
- Fibroblast α11β1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids.PloS one · 2014Article
- 3D time series analysis of cell shape using Laplacian approaches.BMC bioinformatics · 2013Article
- Determinants of maximal force transmission in a motor-clutch model of cell traction in a compliant microenvironment.Biophysical journal · 2013Article
- A computational model for collective cellular motion in three dimensions: general framework and case study for cell pair dynamics.PloS one · 2013Article
- A new candidate substrate for cell-matrix adhesion study: the acellular human amniotic matrix.Journal of biomedicine & biotechnology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell migration is a multi-scale process that integrates signaling, mechanics and biochemical reaction kinetics. Various mathematical models accurately predict cell migration on 2D surfaces, but are unable to capture the complexities of 3D migration. Additionally, quantitative 3D cell migration models have been few and far between. In this review we look and characterize various mathematical models available in literature to predict cell migration in 3D matrices and analyze their strengths and possible changes to these models that could improve their predictive capabilities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.