Evidence map›Paper›PMID 19261940›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Using semantic and structural properties of the Unified Medical Language System to discover potential terminological relationships.

Chintan O Patel, James J Cimino

Erratum issuedAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors.

Chintan O PatelDepartment of Biomedical Informatics, Columbia University, Vanderbilt Clinic, 5 Floor, 622 West 168 Street, New York, NY 10032, USA. chintan.patel@dbmi.columbia.edu
James J Cimino

Funding

Semantic and Machine Learning Methods for Mining Connections in the UMLSR21LM009638 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FRIEDMAN, CAROL · 2007 to 2008
$334k
Intramural NIH HHSNLM NIH HHS R21 LM009638NLM NIH HHS R21LM009638
6 · The paper itself

Abstract

objectiveTo use the semantic and structural properties in the Unified Medical Language System (UMLS) Metathesaurus to characterize and discover potential relationships.

designThe UMLS integrates knowledge from several biomedical terminologies. This knowledge can be used to discover implicit semantic relationships between concepts. In this paper, the authors propose a problem-independent approach for discovering potential terminological relationships that employs semantic abstraction of indirect relationship paths to perform classification and analysis of network theoretical measures such as topological overlap, preferential attachment, graph partitioning, and number of indirect paths. Using different versions of the UMLS, the authors evaluate the proposed approach's ability to predict newly added relationships. MEASUREMENTS: Classification accuracy, precision-recall.

resultsStrong discriminative characteristics were observed with a semantic abstraction based classifier (classification accuracy of 91%), the average number of indirect paths, preferential attachment, and graph partitioning to identify potential relationships. The proposed relationship prediction algorithm resulted in 56% recall in top 10 results for new relationships added to subsequent versions of the UMLS between 2005 and 2007.

conclusionsThe UMLS has sufficient knowledge to enable discovery of potential terminological relationships.

Indexed as

AlgorithmsSubject HeadingsUnified Medical Language SystemClassificationSemanticsVocabulary, Controlled

Identifiers

PMID19261940
PMCPMC3202330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.