Trial reportYonsei medical journal2009
The efficacy of postoperative prophylactic antibiotics in orthognathic surgery: a prospective study in Le Fort I osteotomy and bilateral intraoral vertical ramus osteotomy.
Trial report in Yonsei medical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05852158 (The Use of Single Dose vs Short-Term Peri-Operative Cefazolin in the Prevention of Surgical Site Infection Following Orthognathic Surgery), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Use of Single Dose vs Short-Term Peri-Operative Cefazolin in the Prevention of Surgical Site Infection Following Orthognathic Surgery
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- The outcome of prolonged postoperative antibiotics on wound healing in orthognathic surgery: A meta-analysis.International wound journal · 2023Pooled it
- Evaluation of Prolonged vs Short Courses of Antibiotic Prophylaxis Following Ear, Nose, Throat, and Oral and Maxillofacial Surgery: A Systematic Review and Meta-analysis.JAMA otolaryngology-- head & neck surgery · 2019Pooled it
- Association between prophylactic antibiotics and surgical site infections in bimaxillary orthognathic surgery: a retrospective study.BMC oral health · 2025Article
- Antibiotic Prophylaxis in Maxillofacial Surgery and Evidence-Based Practice: A Systematic Review.Cureus · 2025Review
- Analysis of Risk Factors and Preventive Measures on Postoperative Infection Rates in Orthognathic Surgery Patients: A Retrospective Study.Journal of pharmacy & bioallied sciences · 2025Article
- A Clinical Audit of Surgical Site Infection Surveillance in a Maxillo-Facial and Oral Surgery Unit in an Academic Hospital Complex in South Africa.International wound journal · 2025Observational
- Antibiotic prophylaxis and surgical site infections in orthognathic surgery - a retrospective analysis.BMC oral health · 2023Observational
- Does Penicillin Allergy Increase the Risk of Surgical Site Infection after Orthognathic Surgery? A Multivariate Analysis.Journal of clinical medicine · 2022Article
- Winds of Change in Antibiotic Therapy following Orthognathic Surgery.Medicina (Kaunas, Lithuania) · 2022Article
- Surgical Antimicrobial Prophylaxis and Incidence of Surgical Site Infections at Ethiopian Tertiary-Care Teaching Hospital.Infectious diseases · 2019Article
- Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery.The Cochrane database of systematic reviews · 2015Article
- Value of prophylactic postoperative antibiotic therapy after bimaxillary orthognathic surgery: a clinical trial.Iranian journal of otorhinolaryngology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study examined the efficacy of the postoperative prophylactic antibiotics used in orthognathic surgery. The prevalence of surgical site infections (SSIs) was determined according to the use of postoperative prophylactic antibiotics. PATIENTS AND
methodsFifty-six patients were divided into 2 groups. Each patient intravenously received 1.0 g of a third-generation cephalosporin (Cefpiramide) 30 minutes before surgery. Among them, 28 patients in the control group received 1.0 g Cefpiramide twice daily until the third day after surgery. The postoperative wounds were examined regularly for the presence of infectious signs.
resultsThere was no significant difference in the incidence of postoperative wound infections between patients who had received postoperative prophylactic antibiotic administration and those who had not (p = 0.639).
conclusionProlonged prophylactic antibiotic use after orthognathic surgery may not be necessary, provided that there are no other significant factors for wound infections.
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