ArticleInterdisciplinary perspectives on infectious diseases2008
Interactions of the intestinal epithelium with the pathogen and the indigenous microbiota: a three-way crosstalk.
Article in Interdisciplinary perspectives on infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 59 citations in OpenAlex.
- Review
- Bacterial acetate metabolism and its influence on human epithelia.Emerging topics in life sciences · 2024Review
- Association of lung-intestinal microecology and lung cancer therapy.Chinese medicine · 2023Review
- Article
- The Intestinal Microbiota May Be a Potential Theranostic Tool for Personalized Medicine.Journal of personalized medicine · 2022Review
- GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity.Scientific reports · 2022Article
- Effects of Intestinal Flora on Irritable Bowel Syndrome and Therapeutic Significance of Polysaccharides.Frontiers in nutrition · 2022Review
- Review
- Do acute hepatopancreatic necrosis disease-causing PirABEmerging microbes & infections · 2020Article
- Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles.Scientific reports · 2020Article
- Sustaining exposure to high concentrations of bifidobacteria inhibits gene expression of Mouse's mucosal immunity.Heliyon · 2019Article
- Isolation of Yeasts from Guajillo Pepper (Capsicum annuum L.) Fermentation and Study of Some Probiotic Characteristics.Probiotics and antimicrobial proteins · 2019Article
- Immunological Tolerance and Function: Associations Between Intestinal Bacteria, Probiotics, Prebiotics, and Phages.Frontiers in immunology · 2018Review
- The effects of fermentation products of prebiotic fibres on gut barrier and immune functions in vitro.PeerJ · 2018Article
- Role of gut microbiota in the pathogenesis of colorectal cancer; a review article.Gastroenterology and hepatology from bed to bench · 2018Review
- Fecal microbiome in dogs with inflammatory bowel disease and intestinal lymphoma.The Journal of veterinary medical science · 2017Article
- Specific vaginal lactobacilli suppress the inflammation induced by lipopolysaccharide stimulation through downregulation of toll-like receptor 4 expression in human embryonic intestinal epithelial cells.Bioscience of microbiota, food and health · 2017Article
- Gnotobiotic mouse model's contribution to understanding host-pathogen interactions.Cellular and molecular life sciences : CMLS · 2016Review
- Modulation of microbiota as treatment for intestinal inflammatory disorders: An uptodate.World journal of gastroenterology · 2016Review
- Diarrheal disease and enteric infections in LMIC communities: how big is the problem?Tropical diseases, travel medicine and vaccines · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The mucosal surfaces of the gastrointestinal tract harbor a vast number of commensal microbiota that have coevolved with the host, and in addition display one of the most complex relationships with the host. This relationship affects several important aspects of the biology of the host including the synthesis of nutrients, protection against infection, and the development of the immune system. On the other hand, despite the existence of several lines of mucosal defense mechanisms, pathogenic organisms such as Shigella and Salmonella have evolved sophisticated virulence strategies for breaching these barriers. The constant challenge from these pathogens and the attempts by the host to counter them set up a dynamic equilibrium of cellular and molecular crosstalk. Even slight perturbations in this equilibrium may be detrimental to the host leading to severe bacterial infection or even autoimmune diseases like inflammatory bowel disease. Several experimental model systems, including germ-free mice and antibiotic-treated mice, have been used by various researchers to study this complex relationship. Although it is only the beginning, it promises to be an exciting era in the study of these host-microbe relationships.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.