ArticleOptics express2009
Retinal tumor imaging and volume quantification in mouse model using spectral-domain optical coherence tomography.
Article in Optics express, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed.
- Nanoprobe-Enabled Precision Imaging and Panoramic Boundary Delineation in Retinoblastoma.Cancer innovation · 2026Review
- Early retinal changes in type 2 diabetes detected by texture-based OCT analysis: potential approach for subclinical diabetic retinopathy diagnosis.Eye and vision (London, England) · 2025Article
- Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy.Investigative ophthalmology & visual science · 2025Article
- Biomedical optical imaging technology and applications: From basic research toward clinical diagnosis.Experimental biology and medicine (Maywood, N.J.) · 2020Article
- Retinoblastoma, the visible CNS tumor: A review.Journal of neuroscience research · 2019Review
- Spectropathology-corroborated multimodal quantitative imaging biomarkers for neuroretinal degeneration in diabetic retinopathy.Clinical ophthalmology (Auckland, N.Z.) · 2017Article
- Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma.Molecular vision · 2015Article
- Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development.PloS one · 2014Article
- Effect of contact lens on optical coherence tomography imaging of rodent retina.Current eye research · 2013Article
- Article
- Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.ACS nano · 2013Article
- Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain optical coherence tomography.Investigative ophthalmology & visual science · 2012Article
- Optical coherence tomography: future trends for imaging in glaucoma.Optometry and vision science : official publication of the American Academy of Optometry · 2012Review
- The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties.Investigative ophthalmology & visual science · 2011Article
- Dual-band spectral-domain optical coherence tomography for in vivo imaging the spectral contrasts of the retinal nerve fiber layer.Optics express · 2011Article
- Optical coherence tomography: history, current status, and laboratory work.Investigative ophthalmology & visual science · 2011Review
- Reproducibility of spectral-domain optical coherence tomography total retinal thickness measurements in mice.Investigative ophthalmology & visual science · 2010Article
- Retinal structure of birds of prey revealed by ultra-high resolution spectral-domain optical coherence tomography.Investigative ophthalmology & visual science · 2010Article
- Spectral domain optical coherence tomography in a murine retinal detachment model.Experimental eye research · 2010Article
- Integrated system for combined Raman spectroscopy-spectral domain optical coherence tomography.Journal of biomedical opticsArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
We have successfully imaged the retinal tumor in a mouse model using an ultra-high resolution spectral-domain optical coherence tomography (SD-OCT) designed for small animal retinal imaging. For segmentation of the tumor boundaries and calculation of the tumor volume, we developed a novel segmentation algorithm. The algorithm is based on parametric deformable models (active contours) and is driven by machine learning-based region classification, namely a Conditional Random Field. With this algorithm we are able to obtain the tumor boundaries automatically, while the user can specify additional constraints (points on the boundary) to correct the segmentation result, if needed. The system and algorithm were successfully applied to studies on retinal tumor progression and monitoring treatment effects quantitatively in a mouse model of retinoblastoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.