Evidence map›Paper›PMID 19259129›Full record

ArticleEuropean journal of human genetics : EJHG2009

Y-chromosome distribution within the geo-linguistic landscape of northwestern Russia.

Sheyla Mirabal, Maria Regueiro, Alicia M Cadenas, L Luca Cavalli-Sforza, Peter A Underhill, Dmitry A Verbenko, Svetlana A Limborska, Rene J Herrera

Abstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  16. Afghanistan from a Y-chromosome perspective.European journal of human genetics : EJHG · 2012
    Article
  17. Article
  18. Article
  19. On the origin of Y-chromosome haplogroup N1b.European journal of human genetics : EJHG · 2009
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Sheyla MirabalDepartment of Molecular and Human Genetics, College of Medicine, Florida International University, Miami, FL 33199, USA.
Maria Regueiro
Alicia M Cadenas
L Luca Cavalli-Sforza
Peter A Underhill
Dmitry A Verbenko
Svetlana A Limborska
Rene J Herrera

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Populations of northeastern Europe and the Uralic mountain range are found in close geographic proximity, but they have been subject to different demographic histories. The current study attempts to better understand the genetic paternal relationships of ethnic groups residing in these regions. We have performed high-resolution haplotyping of 236 Y-chromosomes from populations in northwestern Russia and the Uralic mountains, and compared them to relevant previously published data. Haplotype variation and age estimation analyses using 15 Y-STR loci were conducted for samples within the N1b, N1c1 and R1a1 single-nucleotide polymorphism backgrounds. Our results suggest that although most genetic relationships throughout Eurasia are dependent on geographic proximity, members of the Uralic and Slavic linguistic families and subfamilies, yield significant correlations at both levels of comparison making it difficult to denote either linguistics or geographic proximity as the basis for their genetic substrata. Expansion times for haplogroup R1a1 date approximately to 18,000 YBP, and age estimates along with Network topology of populations found at opposite poles of its range (Eastern Europe and South Asia) indicate that two separate haplotypic foci exist within this haplogroup. Data based on haplogroup N1b challenge earlier findings and suggest that the mutation may have occurred in the Uralic range rather than in Siberia and much earlier than has been proposed (12.9+/-4.1 instead of 5.2+/-2.7 kya). In addition, age and variance estimates for haplogroup N1c1 suggest that populations from the western Urals may have been genetically influenced by a dispersal from northeastern Europe (eg, eastern Slavs) rather than the converse.

Indexed as

Polymorphism, GeneticChromosomes, Human, YEthnicityGenetics, PopulationGenotypeGeographyHaplotypesHumansLinguisticsMutationPhylogenyPolymorphism, Single NucleotideRussiaSiberiaTime Factors

Identifiers

PMID19259129
PMCPMC2986641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.