Evidence map›Paper›PMID 19255545›Full record

ArticleMolecules (Basel, Switzerland)2009

Design, synthesis and anti-HIV integrase evaluation of 4-oxo-4H-quinolizine-3-carboxylic acid derivatives.

Yi-Sheng Xu, Cheng-Chu Zeng, Zi-Guo Jiao, Li-Ming Hu, Ru-gang Zhong

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi-Sheng XuBeijing University of Technology, P. R. China. xuys@craes.org.cn
Cheng-Chu Zeng
Zi-Guo Jiao
Li-Ming Hu
Ru-gang Zhong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

4-Oxo-4H-quinolizine-3-carboxylic acid derivatives bearing sulfamido, carboxylamido, benzimidazole and benzothiazole substituents have been designed and synthesized. The structures of these new compounds were confirmed by (1)H-NMR, (13)C- NMR, IR and ESI (or HRMS) spectra. Compounds were screened for possible HIV integrase inhibitory activity.

Indexed as

Carboxylic AcidsHIV Integrase InhibitorsQuinolizinesDrug DesignHIV IntegraseHumansMagnesiumMolecular StructureNuclear Magnetic Resonance, BiomolecularStructure-Activity RelationshipCarboxylic AcidsHIV IntegraseHIV Integrase InhibitorsMagnesiumQuinolizines

Identifiers

PMID19255545
PMCPMC6254011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.