Evidence map›Paper›PMID 19254999›Full record

ArticlePediatrics2009

Pain symptoms and stooling patterns do not drive diagnostic costs for children with functional abdominal pain and irritable bowel syndrome in primary or tertiary care.

Mariella M Lane, Erica M Weidler, Danita I Czyzewski, Robert J Shulman

3 registry-linked trialsOpen access · greenAbstract readComparative Study
In one paragraph

Article in Pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00526903 phase2completednot on this map

Recurrent Abdominal Pain in Children

TypeinterventionalSponsorBaylor College of MedicineRan2009 to 2014Enrolled168ConditionsAbdominal Pain, Irritable Bowel SyndromeArmsElimination Diet
NCT00971711 phase1completednot on this map

Phase I, Open Label Safety Study of VSL#3 in Adults With Irritable Bowel Syndrome

TypeinterventionalSponsorBaylor College of MedicineRan2009 to 2013Enrolled21ConditionsIrritable Bowel SyndromeArmsProbiotic
NCT01204515 completednot on this mapstarted 2010, after this paper: background citation

Abdominal Symptom Phenotype: Pathways to New Biomarkers

TypeobservationalSponsorBaylor College of MedicineRan2010 to 2012Enrolled45ConditionsIrritable Bowel Syndrome (IBS)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Quality of life among parents seeking treatment for their child's functional abdominal pain.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  8. Review
  9. Article
  10. Maintenance of Pain in Children With Functional Abdominal Pain.Journal of pediatric gastroenterology and nutrition · 2016
    Article
  11. Article
  12. Article
  13. Review
  14. Recurrent abdominal pain in childhood.Deutsches Arzteblatt international · 2011
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mariella M LaneTexas Children's Hospital, Psychiatry and Psychology Service, 6621 Fannin St, CC 1740.01, Houston, TX 77030-2399, USA. mmlane@texaschildrenshospital.org
Erica M Weidler
Danita I Czyzewski
Robert J Shulman
Baylor College of Medicine · USMenninger Clinic · USUnited States Department of Agriculture · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
Recurrent Abdominal Pain in ChildrenR01NR005337 · NINR · BAYLOR COLLEGE OF MEDICINE · PI SHULMAN, ROBERT J · 2002 to 2012
$4.3M
NIDDK NIH HHS P30 DK056338NIDDK NIH HHS P30-DK56338NINR NIH HHS R01 NR005337PHS HHS R01-005337
6 · The paper itself

Abstract

objectiveThe objectives of this study were to (1) compare the cost of medical evaluation for children with functional abdominal pain or irritable bowel syndrome brought to a pediatric gastroenterologist versus children who remained in the care of their pediatrician, (2) compare symptom characteristics for the children in primary versus tertiary care, and (3) examine if symptom characteristics predicted the cost of medical evaluation.

methodsEighty-nine children aged 7 to 10 years with functional abdominal pain or irritable bowel syndrome seen by a gastroenterologist (n = 46) or seen only by a pediatrician (n = 43) completed daily pain and stool diaries for 2 weeks. Mothers provided retrospective reports of their children's symptoms in the previous year. Cost of medical evaluation was calculated via chart review of diagnostic tests and application of prices as if the patients were self-pay.

resultsChild-reported diary data reflected no significant group differences with respect to pain, interference with activities, or stool characteristics. In contrast, mothers of children evaluated by a gastroenterologist viewed their children as having higher maximum pain intensity in the previous year. Excluding endoscopy costs, cost of medical evaluation was fivefold higher for children evaluated by a gastroenterologist, with higher cost across blood work, stool studies, breath testing, and diagnostic imaging. Symptom characteristics did not predict cost of care for either group.

conclusionsDespite the lack of difference in symptom characteristics between children in primary and tertiary care, a notable differential in cost of evaluation exists in accordance with level of care. Symptom characteristics do not seem to drive diagnostic evaluation in either primary or tertiary care. Given the lack of differences in child-reported symptoms and the maternal perspective that children evaluated by a gastroenterologist had more severe pain, we speculate that parent perception of child symptoms may be a primary factor in seeking tertiary care.

Indexed as

DefecationAbdominal PainChildColonic Diseases, FunctionalFemaleGastroenterologyHealth Care CostsHumansIrritable Bowel SyndromeLongitudinal StudiesMaleMass ScreeningMedical RecordsPain MeasurementPediatricsPrimary Health Care

Identifiers

PMID19254999
PMCPMC2821591
OpenAlexW2098963714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.