ArticlePediatrics2009
Pain symptoms and stooling patterns do not drive diagnostic costs for children with functional abdominal pain and irritable bowel syndrome in primary or tertiary care.
Article in Pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Recurrent Abdominal Pain in Children
Phase I, Open Label Safety Study of VSL#3 in Adults With Irritable Bowel Syndrome
Abdominal Symptom Phenotype: Pathways to New Biomarkers
Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Children with disorders of gut-brain interaction in primary care versus hospital care: A comparison of characteristics.Journal of pediatric gastroenterology and nutrition · 2025Trial
- Cognitive-behavioral treatment of persistent functional somatic complaints and pediatric anxiety: an initial controlled trial.Depression and anxiety · 2011Trial
- National Medical Expenditures Associated With Pediatric Disorders of Gut-Brain Interaction in the United States.Neurogastroenterology and motility · 2026Article
- Efficacy and Safety of Probiotics in Children with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.Microorganisms · 2025Review
- Healthcare System-to-System Cost Variability in the Care of Pediatric Abdominal Pain-Associated Functional Gastrointestinal Disorders.Children (Basel, Switzerland) · 2021Article
- Initial Diagnosis of Functional Gastrointestinal Disorders in Children Increases a Chance for Resolution of Symptoms.Pediatric gastroenterology, hepatology & nutrition · 2018Article
- Quality of life among parents seeking treatment for their child's functional abdominal pain.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Irritable bowel syndrome in children: Current knowledge, challenges and opportunities.World journal of gastroenterology · 2018Review
- Pediatric Irritable Bowel Syndrome Patient and Parental Characteristics Differ by Care Management Type.Journal of pediatric gastroenterology and nutrition · 2017Article
- Maintenance of Pain in Children With Functional Abdominal Pain.Journal of pediatric gastroenterology and nutrition · 2016Article
- Chronic Abdominal Pain in Children and Adolescents: Parental Threat Perception Plays a Major Role in Seeking Medical Consultations.Pain research & management · 2016Article
- Paediatric gastroenterology: EGD for children with abdominal pain: the jury is still out.Nature reviews. Gastroenterology & hepatology · 2013Article
- Need for a comprehensive medical approach to the neuro-immuno-gastroenterology of irritable bowel syndrome.World journal of gastroenterology · 2011Review
- Recurrent abdominal pain in childhood.Deutsches Arzteblatt international · 2011Review
- Childhood nonspecific abdominal pain in family practice: incidence, associated factors, and management.Annals of family medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe objectives of this study were to (1) compare the cost of medical evaluation for children with functional abdominal pain or irritable bowel syndrome brought to a pediatric gastroenterologist versus children who remained in the care of their pediatrician, (2) compare symptom characteristics for the children in primary versus tertiary care, and (3) examine if symptom characteristics predicted the cost of medical evaluation.
methodsEighty-nine children aged 7 to 10 years with functional abdominal pain or irritable bowel syndrome seen by a gastroenterologist (n = 46) or seen only by a pediatrician (n = 43) completed daily pain and stool diaries for 2 weeks. Mothers provided retrospective reports of their children's symptoms in the previous year. Cost of medical evaluation was calculated via chart review of diagnostic tests and application of prices as if the patients were self-pay.
resultsChild-reported diary data reflected no significant group differences with respect to pain, interference with activities, or stool characteristics. In contrast, mothers of children evaluated by a gastroenterologist viewed their children as having higher maximum pain intensity in the previous year. Excluding endoscopy costs, cost of medical evaluation was fivefold higher for children evaluated by a gastroenterologist, with higher cost across blood work, stool studies, breath testing, and diagnostic imaging. Symptom characteristics did not predict cost of care for either group.
conclusionsDespite the lack of difference in symptom characteristics between children in primary and tertiary care, a notable differential in cost of evaluation exists in accordance with level of care. Symptom characteristics do not seem to drive diagnostic evaluation in either primary or tertiary care. Given the lack of differences in child-reported symptoms and the maternal perspective that children evaluated by a gastroenterologist had more severe pain, we speculate that parent perception of child symptoms may be a primary factor in seeking tertiary care.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.