ReviewPediatric transplantation2009
Lessons from cardiac transplantation in infancy.
Review in Pediatric transplantation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- The immune system in infants: Relevance to xenotransplantation.Pediatric transplantation · 2020Review
- An approach to induction of tolerance to pig cardiac xenografts in neonates.Xenotransplantation · 2018Review
- ABO-incompatible heart transplantation.Current opinion in pediatrics · 2016Review
- B cells in transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2016Article
- Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues.Advances in experimental medicine and biology · 2015Review
- Clinical predictors of autoimmune and severe atopic disease in pediatric heart transplant recipients.Pediatric transplantation · 2014Article
- Heart transplantation for congenital heart disease in the first year of life.Current cardiology reviews · 2011Article
- Challenges in infant immunity: implications for responses to infection and vaccines.Nature immunology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Besides correcting devastating pathophysiology, cardiac transplantation in infancy offers an incomparable model for exploring the structure and function of the immune system. Infants and young children have relatively few memory B cells and T cells. Hence, the response of the young to allotransplantation better represents a primary immune response and may be better suited to testing spontaneous tolerance. Those who undergo cardiac transplantation in infancy are also unique because they are often subjected to thymectomy and depletion of mature T cells. These subjects can have a dramatic contraction of T cell diversity, allowing the testing of how diversity contributes to function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.