ArticleExpert review of anti-infective therapy2009
Filarial parasites in the postgenomic era.
Article in Expert review of anti-infective therapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- The Secretome of Filarial Nematodes and Its Role in Host-Parasite Interactions and Pathogenicity in Onchocerciasis-Associated Epilepsy.Frontiers in cellular and infection microbiology · 2021Review
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Filarial parasites are able to survive for many years in their host, with suppression of the host's immune response being one major survival strategy of the parasite. However, knowledge on molecules that induce these pathways is limited. Additionally, molecules that induce inflammation, thereby leading to severe pathology, such as elephantiasis, are also not fully identified. This article assesses the findings of a recently published analysis of stage-specific excretory-secretory proteins by sodium dodecylsulfate-polyacrylamide gel electrophoresis in combination with liquid chromatography-tandem mass spectrometry. In total, 228 proteins with known and unknown functions were identified and compared with genomic, expressed sequence tags and proteomic databases. We discuss the key findings of this article for implications on filarial parasitism, as well as for a potential use for new therapeutics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.