ArticleMayo Clinic proceedings2009
Carotid intima-media thickness and coronary artery calcium score as indications of subclinical atherosclerosis.
Article in Mayo Clinic proceedings, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Article
- Framingham risk score in predicting increased carotid intima-media thickness on ultrasound: identifying patients with subclinical atherosclerosis at high risk.BMC neurology · 2026Article
- Risk Assessment for Carotid Atherosclerosis in Asymptomatic Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease.Gut and liver · 2026Article
- Cardiovascular rehabilitation in rheumatoid arthritis: evidence and future directions.Rheumatology international · 2025Review
- Atherogenic index of plasma and subclinical vascular disease: predictive value for coronary and carotid atherosclerosis in a health screening population.Lipids in health and disease · 2025Article
- The association between hepatic fibrosis indicators and subclinical carotid atherosclerosis in the population with metabolic dysfunction-associated steatotic liver disease under 50 years old.Nutrition & metabolism · 2025Article
- Advancements in Biomarkers for Early Detection and Risk Stratification of Cardiovascular Diseases-A Literature Review.Health science reports · 2025Article
- Lipids dysregulation in diseases: core concepts, targets and treatment strategies.Lipids in health and disease · 2025Review
- Progression of subclinical cardiovascular disease in patients with HIV.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024Article
- Metabolic dysfunction-associated fatty liver disease: current therapeutic strategies.Frontiers in nutrition · 2024Review
- Cumulative Blood Pressure in Early Adulthood and Coronary Artery Calcium and Carotid Intima-Media Thickness in Middle Age Among Adults With Maintained Blood Pressure of <130/80 mm Hg: A Post Hoc Analysis.Journal of the American Heart Association · 2023Observational
- Risk Scores for Prediction of Major Cardiovascular Events in Non-Alcoholic Fatty Liver Disease: A No Man's Land?Life (Basel, Switzerland) · 2023Review
- Metabolic dysfunction-associated fatty liver disease increased the risk of subclinical carotid atherosclerosis in China.Frontiers in endocrinology · 2023Article
- Evolution and Outcomes of Premature Coronary Artery Disease.Current cardiology reports · 2021Review
- An Overview of the Role of Adipokines in Cardiometabolic Diseases.Molecules (Basel, Switzerland) · 2020Review
- The Impact of Past and Current Alcohol Consumption Patterns on Progression of Carotid Intima-Media Thickness Among Women and Men Living with HIV Infection.Alcoholism, clinical and experimental research · 2019Article
- Time of exposure to night work and carotid atherosclerosis: a structural equation modeling approach using baseline data from ELSA-Brasil.International archives of occupational and environmental health · 2018Article
- Hepatocyte growth factor is associated with progression of atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).Atherosclerosis · 2018Article
- Risk of major adverse cardiovascular events in subjects with asymptomatic mild carotid artery stenosis.Scientific reports · 2018Observational
- Coronary Artery Calcium Scoring in Young Adults: Evidence and Challenges.Current cardiology reports · 2018Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the ability of carotid intima-media thickness (CIMT) and coronary artery calcium score (CACS) to detect subclinical atherosclerosis in a young to middle-aged, low-risk, primary-prevention population. PATIENTS AND
methodsPatients aged 36 to 59 years who underwent determination of CIMT and CACS at our institution between May 1, 2004, and April 1, 2008, were included in the study. Those with diabetes mellitus or a history of coronary, peripheral, or cerebral vascular disease were excluded. Other information, such as Framingham risk score (FRS), was obtained by a review of clinical and laboratory data.
resultsOf 118 patients, 89 (75%) had a CACS of zero and 94 (80%) were men; mean +/- SD age was 48.9+/-5.7 years. The mean FRS of this group was 4.0; 86 patients (97%) were considered at low risk (<1% annualized rate) of cardiovascular events. Evidence of carotid atherosclerosis was found in 42 (47%; 95% confidence interval, 37%-58%) of these 89 patients; carotid plaque was found in 30 (34%); and CIMT above the 75th percentile was found in 12 (13%) of age-, sex-, and race-matched control patients. Of the 40 patients with low-risk CIMT (below the 50th percentile), 4 (10%) had a CACS at or above the 50th percentile.
conclusionSubclinical vascular disease can be detected by CIMT evaluation in young to middle-aged patients with a low FRS and a CACS of zero. These findings have important implications for vascular disease screening and the implementation of primary-prevention strategies.
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