Evidence map›Paper›PMID 19251723›Full record

ReviewCardiovascular research2009

Tetraspanins and vascular functions.

Feng Zhang, Jayaprakash Kotha, Lisa K Jennings, Xin A Zhang

Open access · bronzeAbstract readReview
In one paragraph

Review in Cardiovascular research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Susceptibility ofHeliyon · 2024
    Article
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  11. Article
  12. Review
  13. Article
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  15. Article
  16. Review
  17. Review
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  19. Selective expression of TSPAN2 in vascular smooth muscle is independently regulated by TGF-β1/SMAD and myocardin/serum response factor.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Feng ZhangVascular Biology Center of Excellence, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN 38163, USA.
Jayaprakash Kotha
Lisa K Jennings
Xin A Zhang
University of Tennessee Health Science Center · US

Funding

Molecular Mmechanism of KAI1/CD82-mediated SuppressionR01CA096991 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ZHANG, XIN A · 2004 to 2014
$2.8M
NCI NIH HHS CA-96991
6 · The paper itself

Abstract

Tetraspanins are multiple membrane-spanning proteins that likely function as the organizers of membrane microdomains. Tetraspanins associate with other membrane-bound molecules such as cell-adhesion proteins, growth factor receptors, and Ig superfamily members and regulate key cellular processes such as adhesion, migration, and fusion. Tetraspanins are widely expressed in vascular and haematopoietic cells and are involved in both physiological and pathological processes related to angiogenesis, vascular injury, thrombosis, and haemostasis. A wide body of evidence suggests that tetraspanins directly regulate the development and functions of the vascular system and the pathogenesis of vascular diseases. This article reviews current understanding of the roles of tetraspanins in vascular functions.

Indexed as

Blood VesselsEndothelium, VascularHumansMembrane ProteinsMuscle, Smooth, VascularNeovascularization, PathologicNeovascularization, PhysiologicVascular DiseasesMembrane Proteins

Identifiers

PMID19251723
PMCPMC2695701
OpenAlexW2102019638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.