ReviewHeart rhythm2009
Mechanisms of VF maintenance: wandering wavelets, mother rotors, or foci.
Review in Heart rhythm, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Modeling ventricular tachycardia in genetic long QT syndrome using engineered cardiac tissues.Bioactive materials · 2026Article
- In vivo mapping of human polymorphic ventricular tachycardia.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Mapping and ablation of ventricular fibrillation substrate.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Review
- Mechanistic interpretations of sustained ventricular fibrillation: The role of mapping methodology, model and time.Heart international · 2026Review
- Electrophysiology and Arrhythmogenesis in the Human Right Ventricular Outflow Tract.Circulation. Arrhythmia and electrophysiology · 2022Article
- Ibutilide Reduces Ventricular Defibrillation Threshold and Organizes Ventricular Fibrillation Activation in Canine Heart Failure Model.Cardiovascular drugs and therapy · 2020Article
- The role of the Purkinje network in premature ventricular complex-triggered ventricular fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2018Review
- Endocardial Activation Drives Activation Patterns During Long-Duration Ventricular Fibrillation and Defibrillation.Circulation. Arrhythmia and electrophysiology · 2017Article
- Global Bi-ventricular endocardial distribution of activation rate during long duration ventricular fibrillation in normal and heart failure canines.BMC cardiovascular disorders · 2017Article
- Structural contributions to fibrillatory rotors in a patient-derived computational model of the atria.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2014Article
- Endocardial focal activation originating from Purkinje fibers plays a role in the maintenance of long duration ventricular fibrillation.Croatian medical journal · 2014Article
- Mechanism of reentry induction by a 9-V battery in rabbit ventricles.American journal of physiology. Heart and circulatory physiology · 2014Article
- Rotors and the dynamics of cardiac fibrillation.Circulation research · 2013Review
- Regional cooling facilitates termination of spiral-wave reentry through unpinning of rotors in rabbit hearts.Heart rhythm · 2012Article
- Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine.Journal of the American College of Cardiology · 2011Article
- Mechanisms of defibrillation.Annual review of biomedical engineering · 2010Review
- Purkinje activation precedes myocardial activation following defibrillation after long-duration ventricular fibrillation.Heart rhythm · 2010Article
- High defibrillation threshold: the science, signs and solutions.Indian pacing and electrophysiology journal · 2010Article
- Cardioversion: past, present, and future.Circulation · 2009Article
- Mapping ventricular fibrillation: a simplified experimental model leads to a complicated result.Heart rhythm · 2009Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Ventricular fibrillation (VF), despite its declining incidence as a cause of sudden cardiac death, is still a major health problem. The underlying mechanisms for the maintenance of VF are still disputed. Studies suggest that VF is unlikely one static mechanism but rather a dynamic process of electrical derangement that changes with duration. The 2 principal proposed mechanisms of VF are multiple wavelets and mother rotors. Most studies of these proposed mechanisms for VF maintenance have been during the first minute of VF. However, the time to external defibrillation in the community and pre-hospital settings, where the majority of sudden cardiac death occurs, ranges from 4 to 10 min and the time to defibrillation seems crucial because the odds of survival worsen with delay. Recent studies during the first 10 min of VF suggest that Purkinje fibers are important in maintaining VF after the first 1 to 2 min, either as a part of a reentrant circuit or as a source of focal activations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.