ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2009
Does olfactory function improve after endoscopic sinus surgery?
Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 99 citations in OpenAlex.
- Defining the minimal clinically important difference for olfactory outcomes in the surgical treatment of chronic rhinosinusitis.International forum of allergy & rhinology · 2017Trial
- Investigation of change in cardinal symptoms of chronic rhinosinusitis after surgical or ongoing medical management.International forum of allergy & rhinology · 2015Trial
- Predictors of olfactory dysfunction in rhinosinusitis using the brief smell identification test.The Laryngoscope · 2014Trial
- Effects of functional endoscopic sinus surgery on olfactory and trigeminal function in chronic rhinosinusitis with nasal polyps.Scientific reports · 2026Article
- Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis.The Laryngoscope · 2026Observational
- Olfactory Dysfunction in Chronic Rhinosinusitis: Mechanisms, Diagnosis, and the Role of Endoscopic Sinus Surgery.Journal of clinical medicine · 2026Review
- Importance of Smell Loss to Patients With Chronic Rhinosinusitis With Nasal Polyps: Options for Management and Recovery.Clinical and translational allergy · 2026Review
- Mechanisms, diagnosis, and treatment of olfactory dysfunction in rhinosinusitis.European journal of medical research · 2025Review
- Partial Reversal of Anosmia Following Platinum-Based Chemotherapy in a Patient With Colorectal Adenocarcinoma.Cureus · 2023Article
- Assessment of Olfaction Following Endoscopic Sinus Surgery.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022Review
- Olfactory Change Pattern After Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients.Cureus · 2022Article
- Long-term impact of olfactory dysfunction on daily life.Wiener klinische Wochenschrift · 2021Article
- Olfactory Function After Surgical Treatment of CRS: A Comparison of CRS Patients to Healthy Controls.American journal of rhinology & allergy · 2021Observational
- Olfaction: Sensitive indicator of inflammatory burden in chronic rhinosinusitis.Laryngoscope investigative otolaryngology · 2020Review
- Author's reply to the Letter to the Editor "Prospective evaluation of oral corticosteroid as a predictor of postoperative olfactory recovery after functional endoscopic surgery for nasal polyposis".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- Quality-of-life and olfaction changes observed with short-term medical management of chronic rhinosinusitis.International forum of allergy & rhinology · 2020Observational
- Factors driving olfactory loss in patients with chronic rhinosinusitis: a case control study.International forum of allergy & rhinology · 2020Article
- The treatment efficacy of nasal polyposis on olfactory functions, clinical scoring systems and inflammation markers.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Article
- Diseases of the nasal cavity.Handbook of clinical neurology · 2019Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo examine the impact of endoscopic sinus surgery (ESS) on olfactory impairment in patients with chronic rhinosinusitis (CRS) over intermediate and long-term follow-up. We hypothesized that patients with mild olfactory dysfunction (hyposmia) would benefit from ESS, whereas patients with severe olfactory dysfunction (anosmia) would not. STUDY
designProspective, multi-institutional cohort study. SUBJECTS AND
methodsA total of 111 patients presenting for ESS for treatment of CRS were examined preoperatively, and at 6 and 12 months postoperatively. Demographic, comorbidity, and Smell Identification Test (SIT) data were collected at each time point. Univariate and multivariate analyses were performed.
resultsThe prevalence of gender-adjusted olfactory dysfunction prior to surgery was 67.5 percent. Surprisingly, hyposmic patients did not significantly improve after surgery. In contrast, patients with anosmia significantly improved after ESS (baseline, 6-month SIT scores: 9.7 +/- 2.0, 21.3 +/- 11.2; P = 0.001). Improvement was sustained at 12-month follow-up (21.7 +/- 10.7; P = 0.001). Multivariate linear regression analysis showed that baseline olfactory category and nasal polyposis were significantly associated with improvement in postoperative olfactory function (P = 0.035, P = 0.002).
conclusionContrary to our hypotheses, patients with severe olfactory dysfunction significantly improved after ESS and sustained improvement over time, whereas patients with mild olfactory dysfunction did not.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.