Evidence map›Paper›PMID 19247732›Full record

ReviewCerebellum (London, England)2009

The role of Kv3-type potassium channels in cerebellar physiology and behavior.

Rolf H Joho, Edward C Hurlock

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cerebellum (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Ankyrin-R Links Kv3.3 to the Spectrin Cytoskeleton and Is Required for Purkinje Neuron Survival.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Kv3 KNeuropharmacology · 2018
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rolf H JohoDepartment of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA. rolf.joho@utsouthwestern.edu
Edward C Hurlock
Southwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

Severe Motor Impairment in Kv3 Channel-deficient MiceR01NS042210 · NINDS · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI JOHO, ROLF H. · 2001 to 2004
$1.6M
NINDS NIH HHS NS42210
6 · The paper itself

Abstract

Different subunits of the Kv3 subfamily of voltage-gated potassium (Kv) channels (Kv3.1-Kv3.4) are expressed in distinct neuronal subpopulations in the cerebellum. Behavioral phenotypes in Kv3-null mutant mice such as ataxia with prominent hypermetria and heightened alcohol sensitivity are characteristic of cerebellar dysfunction. Here, we review how the unique biophysical properties of Kv3-type potassium channels, fast activation and fast deactivation that enable cerebellar neurons to generate brief action potentials at high frequencies, affect firing patterns and influence cerebellum-mediated behavior.

Indexed as

Action PotentialsAnimalsBehaviorCerebellumGene ExpressionHumansMiceMice, KnockoutModels, BiologicalMovement DisordersNeuronsProtein SubunitsPsychomotor PerformanceShaw Potassium ChannelsProtein SubunitsShaw Potassium Channels

Identifiers

PMID19247732
OpenAlexW1964276320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.