Evidence map›Paper›PMID 19247271›Full record

Trial reportObesity (Silver Spring, Md.)2009

Resistance training preserves fat-free mass without impacting changes in protein metabolism after weight loss in older women.

Wayne W Campbell, Mark D Haub, Robert R Wolfe, Arny A Ferrando, Dennis H Sullivan, John W Apolzan, Heidi B Iglay

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 72 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. A thermogenic botanical composition containingFood & nutrition research · 2025
    Article
  8. Article
  9. Article
  10. Time-Restricted Eating to Improve Cardiovascular Health.Current atherosclerosis reports · 2021
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Upregulation of circulating myomiR following short-term energy restriction is inversely associated with whole body protein synthesis.American journal of physiology. Regulatory, integrative and comparative physiology · 2017
    Article
  20. Preserving Healthy Muscle during Weight Loss.Advances in nutrition (Bethesda, Md.) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wayne W CampbellDepartment of Foods and Nutrition, Purdue University, West Lafayette, Indiana, USA. campbellw@purdue.edu
Mark D Haub
Robert R Wolfe
Arny A Ferrando
Dennis H Sullivan
John W Apolzan
Heidi B Iglay
Purdue University West Lafayette · USUniversity of Arkansas for Medical Sciences · USKansas State University · US

Funding

Verruca Vulgaris--Skin Test &Candida /Mumps AntigenM01RR014288 · NCRR · UNIV OF ARKANSAS FOR MED SCIS · PI PONNAPPAN, USHA · 1999 to 2006
$11.1M
DIETARY PROTEIN REQUIREMENTS OF ELDERLY MEN AND WOMENR01AG015750 · NIA · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI CAMPBELL, WAYNE W · 1999 to 2002
$1.1M
WEIGHT LOSS AND RESISTANCE TRAINING IN OLDER WOMENR29AG013409 · NIA · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI CAMPBELL, WAYNE W · 1996 to 2000
$77k
NCRR NIH HHS M01 RR014288NCRR NIH HHS MO1 RR14288NIA NIH HHS 1 R01 AG15750NIA NIH HHS 1 R29 AG13409NIA NIH HHS R01 AG015750
6 · The paper itself

Abstract

This study assessed the effects of resistance training (RT) on energy restriction-induced changes in body composition, protein metabolism, and the fractional synthesis rate of mixed muscle proteins (FSRm) in postmenopausal, overweight women. Sixteen women (age 68 +/- 1 years, BMI 29 +/- 1 kg/m(2), mean +/- s.e.m.) completed a 16-week controlled diet study. Each woman consumed 1.0 g protein/kg/day. At baseline (weeks B1-B3) and poststudy (weeks RT12-RT13), energy intake matched each subject's need and during weeks RT1-RT11 was hypoenergetic by 2,092 kJ/day (500 kcal/day). From weeks RT1 to RT13, eight women performed RT 3 day/week (RT group) and eight women remained sedentary (SED group). RT did not influence the energy restriction-induced decrease in body mass (SED -5.8 +/- 0.6 kg; RT -5.0 +/- 0.2 kg) and fat mass (SED -4.1 +/- 0.9 kg; RT -4.7 +/- 0.5 kg). Fat free mass (FFM) and total body water decreased in SED (-1.6 +/- 0.4 and -2.1 +/- 0.5 kg) and were unchanged in RT (-0.3 +/- 0.4 and -0.4 +/- 0.7 kg) (group-by-time, P < or = 0.05 and P = 0.07, respectively). Protein-mineral mass did not change in either group (SED 0.4 +/- 0.2 kg; RT 0.1 +/- 0.4 kg). Nitrogen balance, positive at baseline (2.2 +/- 0.3 g N/day), was unchanged poststudy. After body mass loss, postabsorptive (PA) and postprandial (PP) leucine turnover, synthesis, and breakdown decreased. Leucine oxidation and balance were not changed. PA and total (PA + PP) FSRm in the vastus lateralis were higher after weight loss. RT did not influence these protein metabolism responses. In summary, RT helps older women preserve FFM during body mass loss. The comparable whole-body nitrogen retentions, leucine kinetics, and FSRm between groups are consistent with the lack of differential protein-mineral mass change.

Indexed as

Body Mass IndexResistance TrainingAgedBody CompositionEnergy MetabolismFemaleHumansLeucineMiddle AgedMuscle ProteinsMuscle StrengthNitrogenProteinsWeight LossLeucineMuscle ProteinsNitrogenProteins

Identifiers

PMID19247271
PMCPMC4299870
OpenAlexW2013159270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.