ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2009
Quantitative heel ultrasonography, 25-hydroxyvitamin D, and urine amino-terminal cross-linking telopeptide of type I collagen in patients with a recent hip fracture.
Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study examined quantitative heel ultrasonography (QUS), 25-hydroxyvitamin D (25-OHD) levels, and urine amino-terminal cross-linking telopeptide of type I collagen (NTX-I) levels in patients with a recent osteoporotic hip fracture to see whether they were clinically useful.
methodsStiffness index (SI) T scores from QUS, 25-OHD levels, and urine NTX-I levels were obtained in 53 female and 32 male patients with hip fractures. Sixty-five female patients and 5 male patients attending our geriatric clinic were used for comparison.
resultsThe SI T scores of the hip fracture patients were less than those of the geriatric clinic patients. The difference was significant in female patients (P= .0001) but not in male patients (P= .1). Serum levels of 25-OHD were less than 28 ng/mL in 50 of 59 patients and less than 5 ng/mL in 2 patients. Levels of urine NTX-I were variable and were not correlated with other parameters.
conclusionsPatients who have had a hip fracture have a low SI determined by QUS; this is easy to perform, and it provides a baseline T score from which to assess treatment effects. Most of these patients are vitamin D deficient, and measurement of the 25-OHD level would enable physicians to prescribe an appropriate dose of vitamin D. Urine NTX-I measured shortly after a hip fracture is not clinically helpful.
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