ArticleProceedings of the National Academy of Sciences of the United States of America1991
Physical map of human Xq27-qter: localizing the region of the fragile X mutation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 73 citations in OpenAlex.
- Idiopathic Infertility as a Feature of Genome Instability.Life (Basel, Switzerland) · 2021Review
- Article
- Molecular and genetic analysis of the Drosophila model of fragile X syndrome.Results and problems in cell differentiation · 2012Article
- The systematic functional characterisation of Xq28 genes prioritises candidate disease genes.BMC genomics · 2006Article
- A compositional map of human chromosome band Xq28.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus.The Journal of cell biology · 1995Article
- Myotubular myopathy in a girl with a deletion at Xq27-q28 and unbalanced X inactivation assigns the MTM1 gene to a 600-kb region.American journal of human genetics · 1995Article
- X linked myotubular myopathy (MTM1) maps between DXS304 and DXS305, closely linked to the DXS455 VNTR and a new, highly informative microsatellite marker (DXS1684).Journal of medical genetics · 1994Article
- Identification of tissue-specific expressed sequences in human band Xq28 with complex pig cDNA probes.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Transcriptional organization of a 450-kb region of the human X chromosome in Xq28.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Exclusion of the biglycan (BGN) gene as a candidate gene for the Happle syndrome, employing an intragenic single-strand conformational polymorphism.Human genetics · 1993Article
- Refining the genetic location of the gene for X linked hydrocephalus within Xq28.Journal of medical genetics · 1993Article
- Emery-Dreifuss muscular dystrophy: linkage to markers in distal Xq28.Journal of medical genetics · 1993Article
- Genetic mapping of the X-linked dominant mutations striated (Str) and bare patches (Bpa) to a 600-kb region of the mouse X chromosome: implications for mapping human disorders in Xq28.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
- X-linked nephrogenic diabetes insipidus: from the ship Hopewell to RFLP studies.American journal of human genetics · 1992Article
- Structure and chromosomal localization of the human antidiuretic hormone receptor gene.American journal of human genetics · 1992Article
- Characterization of a deletion at Xq27-q28 associated with unbalanced inactivation of the nonmutant X chromosome.American journal of human genetics · 1992Article
- Further localization of X-linked hydrocephalus in the chromosomal region Xq28.American journal of human genetics · 1992Article
- A 1.6-Mb contig of yeast artificial chromosomes around the human factor VIII gene reveals three regions homologous to probes for the DXS115 locus and two for the DXYS64 locus.American journal of human genetics · 1992Article
- The fragile X syndrome: isolation of the FMR-1 gene and characterization of the fragile X mutation.Chromosoma · 1992Review
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Authors and funding
6 authors at 2 institutions in 4 countries.
Funding
Abstract
We describe a physical map of the end of the long arm of the human X chromosome encompassing the region from Xq27.2 to the q telomere, inclusive of the chromosomal band Xq28. This region is of particular interest, since it contains the highest density of genes associated with genetic diseases. The map covers a total of 12 megabases (Mb) of DNA and extends from the telomere to 3 Mb beyond the most likely position of the fragile X mutation, defined by a cluster of translocation breakpoints in somatic cell hybrids. The map determines order and position of loci throughout the Xq28 region and localizes cell line breakpoints marking the fragile X region to an interval of 300-700 kilobases between 8 and 8.7 Mb proximal of the Xq telomere.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.