ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2009
Changes in symptom clusters in patients undergoing radiation therapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Fear of cancer recurrence trajectory during radiation treatment and follow-up into survivorship of patients with breast cancer.BMC cancer · 2018Trial
- Symptom cluster in patients with resected pancreatic cancer during adjuvant chemotherapy: A cross-sectional study.Asia-Pacific journal of oncology nursing · 2025Article
- Impact of Multimorbidity on Symptom Burden and Symptom Clusters in Patients Receiving Chemotherapy.Cancer medicine · 2025Article
- The dynamic trajectory of symptom networks in patients with acute pancreatitis during hospitalization.Frontiers in medicine · 2025Article
- Study of symptom clusters in brain tumor patients 2 weeks after craniotomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Symptom Clusters and Their Impact on Spiritual Well-Being Among Women with Breast Cancer.International journal of women's health · 2024Article
- Symptom clusters and their predictors in patients with lung cancer and treated with programmed cell death protein 1 immunotherapy.Asia-Pacific journal of oncology nursing · 2022Article
- Prevalence of Insomnia in an Oncology Patient Population: An Irish Tertiary Referral Center Experience.Journal of the National Comprehensive Cancer Network : JNCCN · 2020Article
- Validation and application of a module of the MD Anderson Symptom Inventory for measuring perioperative symptom burden in patients with gynecologic cancer (the MDASI-PeriOp-GYN).Gynecologic oncology · 2019Article
- Temporal patterns of patient-reported trismus and associated mouth-opening distances in radiotherapy for head and neck cancer: A prospective cohort study.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2018Article
- Cytokine Gene Polymorphisms Associated With Symptom Clusters in Oncology Patients Undergoing Radiation Therapy.Journal of pain and symptom management · 2017Article
- Symptom Clusters Change Over Time in Women Receiving Adjuvant Chemotherapy for Breast Cancer.Journal of pain and symptom management · 2017Article
- Advancing Symptom Science Through Symptom Cluster Research: Expert Panel Proceedings and Recommendations.Journal of the National Cancer Institute · 2017Review
- A Factor Analysis Approach for Clustering Patient Reported Outcomes.Methods of information in medicine · 2016Article
- The influence of oxidative stress on symptom occurrence, severity, and distress during childhood leukemia treatment.Oncology nursing forum · 2014Article
- Associations between pro- and anti-inflammatory cytokine genes and breast pain in women prior to breast cancer surgery.The journal of pain · 2012Article
- Cancer-related symptom clusters for symptom management in outpatients after commencing adjuvant chemotherapy, at 6 months, and 12 months.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2012Article
- Article
- Reporting characteristics of cancer pain: a systematic review and quantitative analysis of research publications in palliative care journals.Indian journal of palliative care · 2011Article
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Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
goals of workThe goals of the study were to determine the occurrence rates for and the severity of symptoms at the middle, end, and 1 month after the completion of radiation therapy (RT), to determine the number and types of symptom clusters at these three time points, and to evaluate for changes over time in these symptom clusters. MATERIALS AND
methodsSymptom occurrence and severity were evaluated using the Memorial Symptom Assessment Scale (MSAS) in a sample of patients (n = 160) who underwent RT for breast or prostate cancer. At each time point, an exploratory factor analysis was done to determine the number of symptom clusters (i.e., symptom factors) based on the MSAS symptom severity ratings. MAIN
resultsThe majority of the patients were male and married with a mean age of 61.1 years. The five symptoms with the highest occurrence rates across all three time points were lack of energy, pain, difficulty sleeping, feeling drowsy, and sweats. Although the number of symptoms and the specific symptoms within each symptom cluster were not identical across the three time points, three relatively similar symptom clusters (i.e., "mood-cognitive" symptom cluster, "sickness-behavior" symptom cluster, "treatment-related", or "pain" symptom cluster) were identified in this sample. The internal consistency coefficients for the mood-cognitive symptom cluster and sickness-behavior symptom cluster were adequate at > or =0.68.
conclusionsThree relatively stable symptom clusters were found across RT. The majority of the symptom cluster severity scores were significantly higher in patients with breast cancer compared to patients with prostate cancer.
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