ReviewCurrent opinion in pediatrics2009
Update on successes and challenges regarding mother-to-child transmission of HIV.
Review in Current opinion in pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- Risky behaviours and their correlates among adolescents living with HIV in sub-Saharan Africa: a systematic review.Reproductive health · 2018Pooled it
- Pooled it
- Integrating prevention of mother-to-child HIV transmission (PMTCT) programmes with other health services for preventing HIV infection and improving HIV outcomes in developing countries.The Cochrane database of systematic reviews · 2011Pooled it
- Soccer and Vocational Training are Ineffective Delivery Strategies to Prevent HIV and Substance Abuse by Young, South African Men: A Cluster Randomized Controlled Trial.AIDS and behavior · 2024Trial
- Maternal tuberculosis: a risk factor for mother-to-child transmission of human immunodeficiency virus.The Journal of infectious diseases · 2011Trial
- Political prioritization of prevention of mother-to-child transmission of HIV and syphilis: a qualitative comparative policy analysis in Ghana, Mozambique, and Sudan.Frontiers in public health · 2026Article
- HIV in Children Under 5 years of Age, and its Health Expenditure in Central Asian Countries.Indian journal of pediatrics · 2025Article
- Enhancing Public Health Strategies to Prevent Mother-to-Child Transmission of HIV: Insights from a Cohort Study in Iran.Medical journal of the Islamic Republic of Iran · 2025Article
- Article
- Determinants of mother to child HIV transmission (HIV MTCT); a case control study in governmental health centers of East Gojjam Zone, Northwest Ethiopia, 2019.Reproductive health · 2022Article
- Using the critical path method to rollout and optimise new PMTCT guidelines to eliminate mother-to-child transmission of HIV in Zimbabwe: a descriptive analysis.BMC health services research · 2020Article
- Integrating the prevention of mother-to-child transmission of HIV into primary healthcare services after AIDS denialism in South Africa: perspectives of experts and health care workers - a qualitative study.BMC health services research · 2020Article
- National HIV testing and diagnosis coverage in sub-Saharan Africa: a new modeling tool for estimating the 'first 90' from program and survey data.AIDS (London, England) · 2019Article
- Factors associated with the utilization of antenatal care and prevention of mother-to-child HIV transmission services in Ethiopia: applying a count regression model.BMC women's health · 2018Article
- Women's recall of maternal and newborn interventions received in the postnatal period: a validity study in Kenya and Swaziland.Journal of global health · 2018Article
- Article
- Retention in Care of HIV-Positive Postpartum Females in Kumasi, Ghana.Journal of the International Association of Providers of AIDS Care · 2016Article
- Infectious Diseases of Poverty in Children: A Tale of Two Worlds.Pediatric clinics of North America · 2016Review
- Towards elimination of mother-to-child transmission of HIV in Ghana: an analysis of national programme data.International journal for equity in health · 2016Article
- Women's willingness to be tested for human immunodeficiency virus during pregnancy: A review.World journal of virology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThere is an unprecedented global commitment to reverse the pediatric HIV epidemic by making prevention of mother-to-child transmission (PMTCT) services accessible in all countries. This review outlines the successes made and the challenges that remain. RECENT
findingsIn resource-rich countries, mother-to-child transmission rates of HIV as low as 1% have been achieved. The efficacy of short-course antiretrovirals for PMTCT in Africa is estimated at 50%. Coinfections with herpes simplex virus type 2, other sexually transmitted infections resulting in genital ulcers, and endemic infectious diseases (e.g., malaria) may increase the risk of mother-to-child transmission of HIV. Vertical transmission of drug-resistant viruses has been reported; the prevalence and effect of transmitted resistant virus on treatment outcomes are under investigation. Obstacles facing PMTCT in resource-limited countries include the lack of healthcare infrastructure, limited manpower, and competing public health priorities with the limited healthcare budget. SUMMARY: Although the birth of an HIV-infected child in a resource-rich country is now a sentinel health event, in most resource-limited countries the birth of an HIV-infected child continues to be the status quo. Comprehensive PMTCT, including antiretroviral treatment for HIV-infected women and children, should be paramount in resource-limited countries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.