ArticleHeredity2009
Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory.
Article in Heredity, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 66 citations in OpenAlex.
- Drivers of insect herbivory resistance and tolerance to plant damage in the Brachypodium distachyon species complex.American journal of botany · 2026Article
- Convergence and constraint in glucosinolate evolution across the Brassicaceae.The Plant cell · 2025Article
- Increasing Aridity May Threaten the Maintenance of a Plant Defence Polymorphism.Ecology letters · 2025Article
- Complementing model species with model clades.The Plant cell · 2024Review
- Soil variation among natural habitats alters glucosinolate content in a wild perennial mustard.Journal of experimental botany · 2023Article
- Antagonistic selection and pleiotropy constrain the evolution of plant chemical defenses.Evolution; international journal of organic evolution · 2019Article
- DIACYLGLYCEROL ACYLTRANSFERASE1 Contributes to Freezing Tolerance.Plant physiology · 2018Article
- Plasticity of plant defense and its evolutionary implications in wild populations of Boechera stricta.Evolution; international journal of organic evolution · 2018Article
- Genome-wide association analysis reveals distinct genetic architectures for single and combined stress responses in Arabidopsis thaliana.The New phytologist · 2017Article
- Article
- Effect of Drought on Herbivore-Induced Plant Gene Expression: Population Comparison for Range Limit Inferences.Plants (Basel, Switzerland) · 2016Article
- Flux Control in a Defense Pathway in Arabidopsis thaliana Is Robust to Environmental Perturbations and Controls Variation in Adaptive Traits.G3 (Bethesda, Md.) · 2015Article
- Beyond the thale: comparative genomics and genetics of Arabidopsis relatives.Nature reviews. Genetics · 2015Review
- Article
- Identification of quantitative trait loci and a candidate locus for freezing tolerance in controlled and outdoor environments in the overwintering crucifer Boechera stricta.Plant, cell & environment · 2014Article
- Article
- Strong selection genome-wide enhances fitness trade-offs across environments and episodes of selection.Evolution; international journal of organic evolution · 2014Article
- Review
- Genetic trade-offs and conditional neutrality contribute to local adaptation.Molecular ecology · 2013Article
- A gain-of-function polymorphism controlling complex traits and fitness in nature.Science (New York, N.Y.) · 2012Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
In the Brassicaceae, glucosinolates influence the feeding, reproduction and development of many insect herbivores. Glucosinolate production and effects on herbivore feeding have been extensively studied in the model species, Arabidopsis thaliana and Brassica crops, both of which constitutively produce leaf glucosinolates mostly derived from the amino acid, methionine. Much less is known about the regulation or role in defense of glucosinolates derived from other aliphatic amino acids, such as the branched-chain amino acids (BCAA), valine and isoleucine. We have identified a glucosinolate polymorphism in Boechera stricta controlling the allocation to BCAA- vs methionine-derived glucosinolates in both leaves and seeds. B. stricta is a perennial species that grows in mostly undisturbed habitats of western North America. We have measured glucosinolate profiles and concentrations in 192 F(2) lines that have earlier been used for genetic map construction. We also performed herbivory assays on six F(3) replicates per F(2) line using the generalist lepidopteran, Trichoplusia ni. Quantitative trait locus (QTL) analysis identified a single locus controlling both glucosinolate profile and levels of herbivory, the branched chain-methionine allocation or BCMA QTL. We have delimited this QTL to a small genomic region with a 1.0 LOD confidence interval just 1.9 cm wide, which, in A. thaliana, contains approximately 100 genes. We also found that methionine-derived glucosinolates provided significantly greater defense than the BCAA-derived glucosinolates against feeding by this generalist insect herbivore. The future positional cloning of this locus will allow for testing various adaptive explanations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.