Evidence map›Paper›PMID 19239826›Full record

ReviewCurrent osteoporosis reports2009

Glucocorticoid-induced osteoporosis.

Stuart L Silverman, Nancy E Lane

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 49 citations in OpenAlex.

  1. Effect of vitamin D3 on bone turnover markers in critical illness: post hoc analysis from the VITdAL-ICU study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Trial
  2. Post hoc analysis of a single IV infusion of zoledronic acid versus daily oral risedronate on lumbar spine bone mineral density in different subgroups with glucocorticoid-induced osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012
    Trial
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  6. Observational
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  12. IL-4 administration exerts preventive effects via suppression of underlying inflammation and TNF-α-induced apoptosis in steroid-induced osteonecrosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  13. Article
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  16. Percutaneous vertebroplasty in a series of myasthenic patients with steroid-induced symptomatic vertebral fractures.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013
    Article
  17. Synergistic antiosteoporotic effect of Lepidium sativum and alendronate in glucocorticoid-induced osteoporosis in Wistar rats.African journal of traditional, complementary, and alternative medicines : AJTCAM · 2013
    Article
  18. Article
  19. Effects of glucocorticoid treatment on bone strength.Journal of bone and mineral metabolism · 2010
    Article
  20. ACTH protects against glucocorticoid-induced osteonecrosis of bone.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stuart L SilvermanCedars-Sinai/UCLA and OMC Clinical Research Center, 8641 Wilshire Boulevard, Beverly Hills, CA 90211, USA. stuarts@omcresearch.org
Nancy E Lane
Cedars-Sinai Medical Center · US

Funding

Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Sex Differences in response to an exercise for hyperkyphosisP50AR063043 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GOLD, ELLEN B. · 2012 to 2017
$5.7M
3D IN VIVO MORPHOMETRY OF TRABECULAR MICROSTRUCTURER01AR043052 · NIAMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI LANE, NANCY E · 1995 to 2014
$5.0M
Midcareer Investigator Award Patient-Oriented ResearchK24AR048841 · NIAMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI LANE, NANCY E · 2002 to 2013
$1.4M
NIAMS NIH HHS 2K24 AR 48841NIAMS NIH HHS K24 AR048841NIAMS NIH HHS P50 AR063043NIAMS NIH HHS R01 AR043052NIAMS NIH HHS R01 AR 043052-07NICHD NIH HHS 1K12 HD 051958-01
6 · The paper itself

Abstract

Glucocorticoid treatment can alter bone metabolism, reduce bone strength, and increase the risk for osteoporotic fractures. Risk factors for glucocorticoid-induced osteoporosis (GIO) include older age, high doses, and longer duration of glucocorticoid use. The bone loss that accompanies glucocorticoid use is rapid, and early treatment with bone-sparing agents can prevent bone loss and reduce fracture risk. Several randomized controlled clinical trials have found prevention and treatment of GIO with bisphosphonates, and recently the treatment of GIO with teriparatide, to be effective. This article reviews current information on the epidemiology, pathophysiology, and clinical studies that support using bone-active agents to prevent and treat GIO.

Indexed as

Administration, OralAlendronateBone and BonesBone Density Conservation AgentsCalciumDietary SupplementsDiphosphonatesGlucocorticoidsHumansOsteoporosisTeriparatideVitamin DAlendronateBone Density Conservation AgentsCalciumDiphosphonatesGlucocorticoidsTeriparatideVitamin D

Identifiers

PMID19239826
PMCPMC13592211
OpenAlexW2083168044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.