Evidence map›Paper›PMID 19238589›Full record

ArticleNeurocritical care2009

Transcranial Doppler ultrasonography in the assessment of cerebral circulation arrest: improving sensitivity by transcervical and transorbital carotid insonation and serial examinations.

Alfredo Conti, Domenico G Iacopino, Antonella Spada, Salvatore M Cardali, Maria Giusa, Domenico La Torre, Alfredo Campennì, Olivia Penna, Sergio Baldari, Francesco Tomasello

Abstract read
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In one paragraph

Article in Neurocritical care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Review
  3. Brain death: a clinical overview.Journal of intensive care · 2022
    Review
  4. Brain death and management of the potential donor.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  5. Clinical applications of transcranial Doppler in non-trauma critically ill children: a scoping review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Comparison of cerebral blood flow pattern by transcranial Doppler in patients with diffuse and focal causes of brain death.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012
    Article
  10. Diagnosis of brain death.Neurology international · 2010
    Article
  11. Technical Considerations in the TCD Evaluation of Cerebral Circulatory Arrest in Death by Neurological Criteria.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alfredo ContiDepartment of Neurosurgery, University of Messina, Policlinico Universitario, Via Consolare Valeria 1, 98125, Messina, Italy. alfredo.conti@unime.it.
Domenico G Iacopino
Antonella Spada
Salvatore M Cardali
Maria Giusa
Domenico La Torre
Alfredo Campennì
Olivia Penna
Sergio Baldari
Francesco Tomasello
University of Messina · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTranscranial Doppler (TCD) can detect the cerebral circulation arrest (CCA) in brain death. TCD is highly specific, but less sensitive because of false-negatives accounting for up to 10%. The aim of the study was to explore the diagnostic accuracy of TCD and to determine whether it can be augmented by strategies such as the insonation of the extracranial internal carotid artery (ICA) and sequential examinations.

methodsData of 184 patients, who met clinical criteria of brain death, observed from 1998 through 2006, were retrospectively reviewed. The study of cerebral arteries was performed through the transtemporal approach, suboccipital insonation of the vertebro-basilar system, transorbital insonation of the ICA and ophthalmic artery, and transcervical insonation of the extracranial ICA. Repeated exams were performed in cases of persistent diastolic flow.

resultsThe specificity of the testing was 100%, no false-positive cases were recorded. The sensitivity of conventional TCD examination was 82.1%. The insonation of the extracranial ICA increased sensitivity to 88% allowing the detection of CCA in those patients lacking temporal windows; serial examinations further increased sensitivity to 95.6%.

conclusionsThe addition of insonation of the cervical ICA and of the siphon increased sensitivity of TCD. Nevertheless, a CCA flow patterns may appear later on those segments. Serial examinations, may be needed in those cases.

Indexed as

Ultrasonography, Doppler, TranscranialAdolescentAdultAgedAged, 80 and overBrain DeathCarotid Artery, InternalCerebrovascular CirculationChildChild, PreschoolCohort StudiesHumansInfantMiddle AgedPredictive Value of TestsRegional Blood Flow

Identifiers

PMID19238589
OpenAlexW2137991331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.