ReviewMolecular psychiatry2009
Constitutional mechanisms of vulnerability and resilience to nicotine dependence.
Review in Molecular psychiatry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Trial
- Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement.Molecular medicine (Cambridge, Mass.)Trial
- Cholinergic receptor nicotinic alpha 5 subunit polymorphisms are associated with smoking cessation success in women.BMC medical genetics · 2018Article
- Individual Variations in the Mechanisms of Nicotine Seeking: A Key for Research on Nicotine Dependence.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Article
- Molecular Histochemistry Identifies Peptidomic Organization and Reorganization Along Striatal Projection Units.Biological psychiatry · 2016Article
- Are tobacco dependence and withdrawal related amongst heavy smokers? Relevance to conceptualizations of dependence.Journal of abnormal psychology · 2012Article
- Impaired goal-directed behavioural control in human impulsivity.Quarterly journal of experimental psychology (2006) · 2012Article
- Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model.Human molecular genetics · 2011Article
- Deconstructing craving: dissociable cortical control of cue reactivity in nicotine addiction.Biological psychiatry · 2011Article
- Association of the MAOA promoter uVNTR polymorphism with suicide attempts in patients with major depressive disorder.BMC medical genetics · 2011Article
- Emergence of dormant conditioned incentive approach by conditioned withdrawal in nicotine addiction.Biological psychiatry · 2010Article
- N-methyl-D-aspartic acid receptors on striatal neurons are essential for cocaine cue reactivity in mice.Biological psychiatry · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The core nature of nicotine dependence is evident in wide variations in how individuals become and remain smokers. Individuals with pre-existing behavioral traits are more likely to develop nicotine dependence and experience difficulty when attempting to quit. Many molecular factors likely contribute to individual variations in the development of nicotine dependence and behavioral traits in complex manners. However, the identification of such molecules has been hampered by the phenotypic complexity of nicotine dependence and the complex ways molecules affect elements of nicotine dependence. We hypothesize that nicotine dependence is, in part, a result of interactions between nicotine and pre-existing behavioral traits. This perspective suggests that the identification of the molecular bases of such pre-existing behavioral traits will contribute to the development of effective methods for reducing smoking dependence and for helping smokers to quit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.