ReviewHuman immunology2009
Therapeutic potential of FOXP3(+) regulatory T cells and their interactions with dendritic cells.
Review in Human immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- CCR6 blockade on regulatory T cells ameliorates experimental model of multiple sclerosis.Central-European journal of immunology · 2020Article
- Turning the Tide Against Regulatory T Cells.Frontiers in oncology · 2019Review
- CD4+Foxp3+T Regulatory Cells Promote Transplantation Tolerance by Modulating Effector CD4+ T Cells in a Neuropilin-1-Dependent Manner.Frontiers in immunology · 2019Article
- Expression of CD11a in lymphocyte subpopulation in immune thrombocytopenia.International journal of clinical and experimental pathology · 2015Article
- Regulatory T cell microRNA expression changes in children with acute Kawasaki disease.Clinical and experimental immunology · 2014Article
- Timing and intensity of exposure to interferon-γ critically determines the function of monocyte-derived dendritic cells.Immunology · 2014Article
- Th17 cells and Tregs: unlikely allies.Journal of leukocyte biology · 2014Review
- In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo.Cytokine · 2014Article
- Peripheral and thymic foxp3(+) regulatory T cells in search of origin, distinction, and function.Frontiers in immunology · 2013Article
- Article
- Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity.Oncotarget · 2012Review
- Immunotherapy of rat glioma without accumulation of CD4(+)CD25(+)FOXP3(+) regulatory T cells.Neural regeneration research · 2012Article
- Peripheral T regulatory cells and cytokines in hepatitis E infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32).BMC biochemistry · 2011Article
- Oral tolerance.Immunological reviews · 2011Review
- The dendritic cell-regulatory T lymphocyte crosstalk contributes to tumor-induced tolerance.Clinical & developmental immunology · 2011Review
- The role of regulatory T cells in atopic dermatitis.Current problems in dermatology · 2011Review
- An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- The T helper type 17/regulatory T cell imbalance in patients with acute Kawasaki disease.Clinical and experimental immunology · 2010Article
- Overexpression of TGF-ß 1 gene induces cell surface localized glucose-regulated protein 78-associated latency-associated peptide/TGF-ß.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
FOXP3(+) regulatory T cells, a unique subset of T cells, are critical for orchestrating an immune response and preventing self-reactivity. With the increasing prevalence and unsatisfactory treatment of autoimmunity, allergic diseases, cancer and chronic infections, much attention has been focused on understanding their mechanisms of action in order to manipulate their function. One goal is to develop drugs or biologics that can enhance or abrogate their functions. Another approach is to utilize Tregs in adoptive cell-based therapy to treat autoimmune diseases or transplant-related complications. This review will focus on their therapeutic potential and mechanisms of action, particularly their interaction with dendritic cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.