ArticleMolecular vision2009
PDCD1 genes may protect against extraocular manifestations in Chinese Han patients with Vogt-Koyanagi-Harada syndrome.
Article in Molecular vision, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Association of HLA-DR4/HLA-DRB1*04 with Vogt-Koyanagi-Harada disease: a systematic review and meta-analysis.Scientific reports · 2014Pooled it
- Polymorphisms and Circulating Plasma Protein Levels of Immune Checkpoints (CTLA-4 and PD-1) Are Associated With Posner-Schlossman Syndrome in Southern Chinese.Frontiers in immunology · 2021Article
- Treatment of Vogt-Koyanagi-Harada Disease.Cureus · 2020Article
- Association of PDCD1 gene markers with susceptibility to thyroid cancer.Journal of endocrinological investigation · 2017Article
- Expression and role of interleukin-9 in Vogt-Koyanagi-Harada disease.Molecular vision · 2017Article
- CFI-rs7356506 polymorphisms associated with Vogt-Koyanagi-Harada syndrome.Molecular vision · 2016Article
- A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China.International journal of genomics · 2014Article
- Gender differences in vogt-koyanagi-harada disease and sympathetic ophthalmia.Journal of ophthalmology · 2014Review
- Influence of molecular genetics in Vogt-Koyanagi-Harada disease.Journal of ophthalmic inflammation and infection · 2014Review
- Programmed death-1 gene polymorphism (PD-1.5 C/T) is associated with gastric cancer.Gastroenterology and hepatology from bed to bench · 2013Article
- Polymorphisms in PDCD1 gene are not associated with aplastic anemia in Chinese Han population.Rheumatology international · 2012Article
- Program death 1 (PD1) haplotyping in patients with breast carcinoma.Molecular biology reports · 2011Article
- Programmed cell death 1 gene polymorphisms is associated with ankylosing spondylitis in Chinese Han population.Rheumatology international · 2011Article
- Evaluation of NLRP1 gene polymorphisms in Vogt-Koyanagi-Harada disease.Japanese journal of ophthalmology · 2011Article
- Lack of an association of PD-1 and its ligand genes with Behcet's disease in a Chinese Han population.PloS one · 2011Article
- Association between hepatitis B viral burden in chronic infection and a functional single nucleotide polymorphism of the PDCD1 gene.Journal of clinical immunology · 2010Article
- Monocyte chemoattractant protein (MCP)-1 -2518 A/G SNP in Chinese Han patients with VKH syndrome.Molecular vision · 2009Article
- Evaluation of PTPN22 polymorphisms and Vogt-Koyanagi-Harada disease in Japanese patients.Molecular vision · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze the potential association of programmed cell death 1 (PDCD1) with Vogt-Koyanagi-Harada (VKH) syndrome in a Chinese Han population.
methodsThree single nucleotide polymorphism (SNPs), PD-1.3G/A, PD-1.5C/T, and PD-1.6G/A, were genotyped in 247 VKH patients and 289 age-, sex-, and ethnically-matched healthy controls using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. The associations of genotypes and alleles with VKH syndrome were analyzed.
resultsAll genotype distributions in healthy controls were in Hardy-Weinberg equilibrium. The genotype and allele frequencies of PD-1.3, PD-1.5, and PD-1.6 were not different between patients with VKH syndrome and healthy controls. No significant difference was observed according to the status of human leukocyte antigen (HLA)-DR4 and HLA-DRw53. Compared to the controls, lower frequencies of the PD-1.5C genotype and allele frequencies were observed in VKH patients with extraocular findings.
conclusionsPD-1.3 and PD-1.6 polymorphisms are not associated with the susceptibility to VKH syndrome in the Chinese Han population. However, PD-1.5 may be negatively associated with the occurrence of extraocular manifestations of VKH syndrome.
Indexed as
Identifiers
19234630PMC2645903W2116096130What OpenQuestion holds
Registered trials
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