Evidence map›Paper›PMID 19234518›Full record

ReviewBiochemistry and cell biology = Biochimie et biologie cellulaire2009

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment.

Gary S Stein, Sayyed K Zaidi, Janet L Stein, Jane B Lian, Andre J van Wijnen, Martin Montecino, Daniel W Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi and 3 more

Abstract readReview
In one paragraph

Review in Biochemistry and cell biology = Biochimie et biologie cellulaire, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gary S SteinDepartment of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655-0002, USA. gary.stein@umassmed.edu
Sayyed K Zaidi
Janet L Stein
Jane B Lian
Andre J van Wijnen
Martin Montecino
Daniel W Young
Amjad Javed
Jitesh Pratap
Je-Yong Choi
Syed A Ali
Sandhya Pande
Mohammad Q Hassan

Funding

SUBNUCLEAR TARGETING OF TRANSCRIPTION FACTORSP01CA082834 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STEIN, GARY S. · 2001 to 2015
$18.4M
Subnuclear Integration of Regulatory Signals Controlling Bone Cell FunctionP01AR048818 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STEIN, JANET L · 2002 to 2011
$14.0M
Molecular Control of Bone FormationR01AR049069 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WESTENDORF, JENNIFER J · 2003 to 2021
$5.8M
NCI NIH HHS CA82834NCI NIH HHS P01 CA082834NIAMS NIH HHS AR48818NIAMS NIH HHS P01 AR048818NIAMS NIH HHS R01 AR049069
6 · The paper itself

Abstract

Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.

Indexed as

Epigenesis, GeneticAnimalsCell LineageCell NucleusCell ProliferationHumansMitosisTranscription FactorsTranscription Factors

Identifiers

PMID19234518
PMCPMC2708786

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.