ReviewDNA repair2009
Genome stability roles of SUMO-targeted ubiquitin ligases.
Review in DNA repair, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- GNL3 SUMOylation is essential for DNA double-strand break repair by homologous recombination.Nature communications · 2026Article
- Review
- Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells.Oncogene · 2019Article
- SUMO Chains Rule on Chromatin Occupancy.Frontiers in cell and developmental biology · 2019Review
- Antiestrogens: structure-activity relationships and use in breast cancer treatment.Journal of molecular endocrinology · 2017Review
- Functional Crosstalk between the PP2A and SUMO Pathways Revealed by Analysis of STUbL Suppressor, razor 1-1.PLoS genetics · 2016Article
- Cooperativity of the SUMO and Ubiquitin Pathways in Genome Stability.Biomolecules · 2016Review
- Pli1(PIAS1) SUMO ligase protected by the nuclear pore-associated SUMO protease Ulp1SENP1/2.The Journal of biological chemistry · 2015Article
- Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4).The Journal of biological chemistry · 2015Article
- Article
- RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.EMBO reports · 2014Article
- Exploring the RING-catalyzed ubiquitin transfer mechanism by MD and QM/MM calculations.PloS one · 2014Article
- Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation.Molecular and cellular biology · 2013Article
- Role of RNF4 in the ubiquitination of Rta of Epstein-Barr virus.The Journal of biological chemistry · 2013Article
- Sumoylation and the DNA damage response.Biomolecules · 2012Review
- SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage.Genes & development · 2012Article
- Changing the ubiquitin landscape during viral manipulation of the DNA damage response.FEBS letters · 2011Review
- DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes.Molecular and cellular biology · 2011Article
- Coordinate to guard: crosstalk of phosphorylation, sumoylation, and ubiquitylation in DNA damage response.Frontiers in oncology · 2011Article
- Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SAD.Journal of cellular physiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Post-translational modification of the cell's proteome by ubiquitin and ubiquitin-like proteins provides dynamic functional regulation. Ubiquitin and SUMO are well-studied post-translational modifiers that typically impart distinct effects on their targets. The recent discovery that modification by SUMO can target proteins for ubiquitination and proteasomal degradation sets a new paradigm in the field, and offers insights into the roles of SUMO and ubiquitin in genome stability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.