Evidence map›Paper›PMID 19233638›Full record

ReviewCurrent opinion in biotechnology2009

Advances in bioluminescence imaging of live animal models.

Robin S Dothager, Kelly Flentie, Britney Moss, Mei-Hsiu Pan, Aparna Kesarwala, David Piwnica-Worms

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Introducing a new reporter gene, membrane-anchoredMolecular therapy oncolytics · 2021
    Article
  10. Article
  11. Review
  12. Glucuronidation of D-Luciferin In Vitro: Isoform Selectivity and Kinetics Characterization.European journal of drug metabolism and pharmacokinetics · 2019
    Article
  13. Article
  14. Frontiers in aging neuroscience · 2019
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Design and Synthesis of an Alkynyl Luciferin Analogue for Bioluminescence Imaging.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robin S DothagerMolecular Imaging Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. dothagerr@mir.wustl.edu
Kelly Flentie
Britney Moss
Mei-Hsiu Pan
Aparna Kesarwala
David Piwnica-Worms

Funding

WU-MDACC Inter-Institutional Molecular Imaging CenterP50CA094056 · NCI · WASHINGTON UNIVERSITY · PI KOPAN, RAPHAEL · 2002 to 2016
$26.3M
NCI NIH HHS P50 CA094056NCI NIH HHS P50 CA94056
6 · The paper itself

Abstract

Many of the obligate steps of physiology and disease are dynamic in time and space, and thus, end-point assays do not always provide a full understanding of these processes. Comprehensive understanding of the functional complexity of protein interactions and cell trafficking requires mapping of cellular and molecular function within complex systems over biologically relevant time scales. New approaches to bioluminescence imaging of cell migration, signaling pathways, drug action, and interacting protein partners in vivo allow the study of biology and disease within the context of living animals.

Indexed as

AnimalsCardiovascular DiseasesCommunicable DiseasesDiagnostic ImagingDisease Models, AnimalLuminescent MeasurementsNeoplasms

Identifiers

PMID19233638
PMCPMC2680462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.