ArticleJournal of psychiatric research2009
Evaluation of behavioral impulsivity and aggression tasks as endophenotypes for borderline personality disorder.
Article in Journal of psychiatric research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 155 citations in OpenAlex.
- Inhibitory control deficits in borderline personality disorder: a meta-analysis of stop-signal and Go/No-Go tasks.Psychological medicine · 2025Pooled it
- Aggression in borderline personality disorder: evidence for increased risk and clinical predictors.Current psychiatry reports · 2012Pooled it
- Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Trial
- The relation of borderline personality disorder to aggression, victimization, and institutional misconduct among prisoners.Comprehensive psychiatry · 2018Trial
- Frontolimbic neural circuit changes in emotional processing and inhibitory control associated with clinical improvement following transference-focused psychotherapy in borderline personality disorder.Psychiatry and clinical neurosciences · 2016Trial
- Zolmitriptan and human aggression: interaction with alcohol.Psychopharmacology · 2010Trial
- Identifying affective state via clustering of temporal variability in limbic activity and mediating role of negative emotion.Molecular psychiatry · 2026Article
- Human tears as social chemo-signals in taming male aggression.Journal of biosciences · 2026Article
- [Gender differences in aggression associated with mental disorders : A narrative literature review].Der Nervenarzt · 2026Review
- Cognitive Control Decision-Making Dynamics Across Internalizing and Externalizing Symptoms in Youth.Research on child and adolescent psychopathology · 2025Article
- Modulating interhemispheric prefrontal dynamics of aggressive behavior: Sex differences and the association with personal disposition.Cognitive, affective & behavioral neuroscience · 2025Article
- Characterizing the role of impulsivity in costly, reactive aggression using a novel paradigm.Behavior research methods · 2024Article
- Network Analysis of Borderline Personality Features in Adolescence Using a Screening Tool in a Chinese Community Sample.Psychopathology · 2024Article
- Investigating proactive aggression in patients with borderline personality disorder and major depressive disorder using a modified version of the Taylor aggression paradigm.Frontiers in psychology · 2024Article
- Etiopathogenesis in the Development of Borderline Personality Characteristics in Children and Adolescents.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2024Review
- The Effect of Social Situations on Risky Decision-Making in Individuals With Borderline Personality Tendency.Psychiatry investigation · 2023Article
- Can we rewire criminal mind via non-invasive brain stimulation of prefrontal cortex? Insights from clinical, forensic and social cognition studies.Current psychology (New Brunswick, N.J.) · 2022Article
- An exploratory study of problematic shopping and problematic video gaming in adolescents.PloS one · 2022Article
- Assessing reactive violence using Immersive Virtual Reality.PloS one · 2022Article
- Impaired impulse inhibition of emotional stimuli in patients with borderline personality disorder.Scientific reports · 2021Article
Corrections and comments
- Commented on by
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Borderline personality disorder (BPD) is marked by aggression and impulsive, often self-destructive behavior. Despite the severe risks associated with BPD, relatively little is known about the disorder's etiology. Identification of genetic correlates (endophenotypes) of BPD would improve the prospects of targeted interventions for more homogeneous subsets of borderline patients characterized by specific genetic vulnerabilities. The current study evaluated behavioral measures of aggression and impulsivity as potential endophenotypes for BPD. Subjects with BPD (N=127), a non cluster B personality disorder (OPD N=122), or healthy volunteers (HV N=112) completed self report and behavioral measures of aggression, motor impulsivity and cognitive impulsivity. Results showed that BPD subjects demonstrated more aggression and motor impulsivity than HV (but not OPD) subjects on behavioral tasks. In contrast, BPD subjects self-reported more impulsivity and aggression than either comparison group. Subsequent analyses showed that among BPD subjects behavioral aggression was associated with self-reported aggression, while behavioral and self-report impulsivity measures were more modestly associated. Overall, the results provide partial support for the use of behavioral measures of aggression and motor impulsivity as endophenotypes for BPD, with stronger support for behavioral aggression measures as an endophenotype for aggression within BPD samples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.