ReviewArthritis research & therapy2009
Transcription profiling of rheumatic diseases.
Review in Arthritis research & therapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.Arthritis research & therapy · 2014Trial
- A systematic review of CXCL13 as a biomarker of disease and treatment response in rheumatoid arthritis.BMC rheumatology · 2020Article
- An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis.PLoS computational biology · 2019Article
- The clinical utility of gene expression examination in rheumatology.Mediterranean journal of rheumatology · 2017Review
- Is there a role of synovial biopsy in drug development?BMC musculoskeletal disorders · 2016Review
- Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.Arthritis research & therapy · 2014Article
- Feline degenerative joint disease: a genomic and proteomic approach.Journal of feline medicine and surgery · 2013Article
- Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.The Journal of experimental medicine · 2013Article
- Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?PloS one · 2013Article
- DNA methylome signature in rheumatoid arthritis.Annals of the rheumatic diseases · 2013Article
- Cold and heat pattern of rheumatoid arthritis in traditional Chinese medicine: distinct molecular signatures indentified by microarray expression profiles in CD4-positive T cell.Rheumatology international · 2012Article
- Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis.Arthritis research & therapy · 2011Article
- Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases.Arthritis research & therapy · 2011Article
- Utility of physiologically based absorption modeling in implementing Quality by Design in drug development.The AAPS journal · 2011Article
- Clinical trials: Tight control in early RA pays off in the long run.Nature reviews. Rheumatology · 2010Article
- Article
- Overview of electrochemical DNA biosensors: new approaches to detect the expression of life.Sensors (Basel, Switzerland) · 2009Article
- HDAC inhibition in lupus models.Molecular medicine (Cambridge, Mass.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Rheumatic diseases are a diverse group of disorders. Most of these diseases are heterogeneous in nature and show varying responsiveness to treatment. Because our understanding of the molecular complexity of rheumatic diseases is incomplete and criteria for categorization are limited, we mainly refer to them in terms of group averages. The advent of DNA microarray technology has provided a powerful tool to gain insight into the molecular complexity of these diseases; this technology facilitates open-ended survey to identify comprehensively the genes and biological pathways that are associated with clinically defined conditions. During the past decade, encouraging results have been generated in the molecular description of complex rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome and systemic sclerosis. Here, we describe developments in genomics research during the past decade that have contributed to our knowledge of pathogenesis, and to the identification of biomarkers for diagnosis, patient stratification and prognostication.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.