Evidence map›Paper›PMID 19231607›Full record

ReviewPrimary care2009

Depression in childbearing women: when depression complicates pregnancy.

Sheila M Marcus, Julie E Heringhausen

Registry-linked trialAbstract readReview
In one paragraph

Review in Primary care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02566980 (The Role of Kynurenine Pathway Metabolites in Perinatal Depression and Suicidality), which is not on this map. Cited by 52 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02566980 completednot on this mapstarted 2014, after this paper: background citation

The Role of Kynurenine Pathway Metabolites in Perinatal Depression and Suicidality

TypeobservationalSponsorMichigan State UniversityRan2014 to 2017Enrolled209ConditionsDepression and Suicide, Mood Disorders, Other Perinatal Conditions
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Understanding depressive symptoms among high-risk, pregnant, African-American women.Women's health issues : official publication of the Jacobs Institute of Women's Health
    Trial
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Neuroactive steroid biosynthesis during pregnancy predicts future postpartum depression: a role for the 3α and/or 3β-HSD neurosteroidogenic enzymes?Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sheila M MarcusDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, Ann Arbor, MI 48109, USA. smmarcus@umich.edu
Julie E Heringhausen

Funding

Infant Outcomes and Depression Treatment in PregnancyR21MH072673 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARCUS, SHEILA MARIE · 2006 to 2007
$371k
NIMH NIH HHS R21 MH072673
6 · The paper itself

Abstract

Prevalence studies show that one in five women experience an episode of major depressive disorder during their lifetime. It is important for health care providers to be aware of (1) the frequency of depression in this population; (2) signs, symptoms, and appropriate screening methods; and (3) health risks for the mother and growing fetus if depression is undetected or untreated. Because management of depressed pregnant women also includes care of a growing fetus, treatment may be complicated and primary care providers should consider a multidisciplinary approach, including an obstetrician, psychiatrist, and pediatrician, to provide optimal care.

Indexed as

Maternal WelfareWomen's HealthAntidepressive AgentsDepressionDepression, PostpartumFemaleHumansPregnancyPregnancy ComplicationsPrevalencePsychotherapyRisk FactorsUnited StatesAntidepressive Agents

Identifiers

PMID19231607
PMCPMC2680254

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.