Evidence map›Paper›PMID 19231593›Full record

ReviewAdvances in immunology2009

Biology of the eosinophil.

Carine Blanchard, Marc E Rothenberg

Abstract readReview
In one paragraph

Review in Advances in immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
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  6. Review
  7. Article
  8. Review
  9. Review
  10. Biological Therapies in Chronic Obstructive Pulmonary Disease: New Directions in Personalised Respiratory Medicine.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Myeloid cells in chronic liver inflammation.Cellular & molecular immunology · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carine BlanchardDivision of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229-3039, USA.
Marc E Rothenberg

Funding

TSLP, IL-9-producing mucosal mast cells, and allergic inflammationU19AI070235 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Marc E. Rothenberg · 2006 to 2026
$31.3M
REGULATION OF GASTROINTESTINAL EOSINOPHILSR01AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 1999 to 2024
$4.5M
Regulation of Gastrointestinal EosinophilsR37AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2010 to 2019
$3.6M
IL-13 and Eosinophilic EsophagitisR01DK076893 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2007 to 2011
$3.1M
Molecular-Genetic Mechs Underlying Effects of Anti-inflammatory/Analgesic DrugsZ01NR000014 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI DIONNE, RAYMOND A · 2006 to 2008
$1.8M
TSG6 in IgE mediated Food AllergyR21AI079874 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI BLANCHARD, CARINE · 2008 to 2009
$375k
NIAID NIH HHS AI070235NIAID NIH HHS AI079874-01NIAID NIH HHS AI45898NIAID NIH HHS R01 AI045898NIAID NIH HHS R21 AI079874NIAID NIH HHS R37 AI045898NIAID NIH HHS U19 AI070235NIDDK NIH HHS DK076893NIDDK NIH HHS P30 DK0789392NIDDK NIH HHS R01 DK076893
6 · The paper itself

Abstract

In this review, we aim to put in perspective the biology of a multifunctional leukocyte, the eosinophil, by placing it in the context of innate and adaptive immune responses. Eosinophils have a unique contribution in initiating inflammatory and adaptive responses, due to their bidirectional interactions with dendritic cells and T cells, as well as their large panel of secreted cytokines and soluble mediators. The mechanisms and consequences of eosinophil responses in experimental inflammatory models and human diseases are discussed.

Indexed as

AnimalsAntigen PresentationBacterial InfectionsCell Adhesion MoleculesCytokinesEosinophil Cationic ProteinEosinophil-Derived NeurotoxinEosinophil Major Basic ProteinEosinophilsHumansHypersensitivityIntegrinsLymphocyte Function-Associated Antigen-1Macrophage-1 AntigenMast CellsPeroxidaseCell Adhesion MoleculesCytokinesEosinophil Cationic ProteinEosinophil-Derived NeurotoxinEosinophil Major Basic Proteinintegrin alpha4beta7IntegrinsLymphocyte Function-Associated Antigen-1Macrophage-1 AntigenPeroxidase

Identifiers

PMID19231593
PMCPMC4109275

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.