ArticleWorld journal of gastroenterology2009
Diagnostic model of saliva protein finger print analysis of patients with gastric cancer.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Salivary biomarkers for diagnosis of systemic diseases and malignant tumors. A systematic review.Medicina oral, patologia oral y cirugia bucal · 2020Pooled it
- Defining salivary biomarkers using mass spectrometry-based proteomics: a systematic review.Omics : a journal of integrative biology · 2011Pooled it
- Salivary biomarkers for cancer diagnosis: a meta-analysis.Annals of medicinePooled it
- Cytoskeleton Remodeling-Related Proteins Represent a Specific Salivary Signature in PSC Patients.Molecules (Basel, Switzerland) · 2024Article
- Salivary metabolomic biomarkers for esophageal and gastric cancers by liquid chromatography-mass spectrometry.Cancer science · 2024Article
- Salivary proteomics profiling reveals potential biomarkers for chronic kidney disease: a pilot study.Frontiers in medicine · 2024Article
- Biomarkers in Cancer Detection, Diagnosis, and Prognosis.Sensors (Basel, Switzerland) · 2023Review
- A salivary biomarker panel to detect liver cirrhosis.iScience · 2023Article
- Applications of Mass Spectrometry in Dentistry.Biomedicines · 2023Review
- Childhood Allergy Disease, Early Diagnosis, and the Potential of Salivary Protein Biomarkers.Mediators of inflammation · 2021Review
- Salivary KLK5 and uPA are potential biomarkers for malignant transformation of OLK and OLP.Cancer biomarkers : section A of Disease markers · 2021Article
- Salivary exosomes: properties, medical applications, and isolation methods.Molecular biology reports · 2020Review
- Validation of Salivary Markers, IL-1β, IL-8 and Lgals3bp for Detection of Oral Squamous Cell Carcinoma in an Indian Population.Scientific reports · 2020Article
- Liquid Biopsy as Novel Tool in Precision Medicine: Origins, Properties, Identification and Clinical Perspective of Cancer's Biomarkers.Diagnostics (Basel, Switzerland) · 2020Review
- Salivary Exosomes as Nanocarriers for Cancer Biomarker Delivery.Materials (Basel, Switzerland) · 2019Review
- Protein-Protein Interaction Network Analysis of Salivary Proteomic Data in Oral Cancer CasesAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Salivary biomarkers in cancer detection.Medical oncology (Northwood, London, England) · 2017Review
- Cancer Salivary Biomarkers for Tumours Distant to the Oral Cavity.International journal of molecular sciences · 2016Review
- Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection.Scientific reports · 2016Article
- Diagnostic model of saliva peptide finger print analysis of oral squamous cell carcinoma patients using weak cation exchange magnetic beads.Bioscience reports · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the method for early diagnosis of gastric cancer by screening the expression spectrum of saliva protein in gastric cancer patients using mass spectrometry for proteomics.
methodsProportional peptide mass fingerprints were obtained by analysis based on proteomics matrix-assisted laser desorption ionization time-of-flight/mass spectrometry. A diagnosis model was established using weak cation exchange magnetic beads to test saliva specimens from gastric cancer patients and healthy subjects.
resultsSignificant differences were observed in the mass to charge ratio (m/z) peaks of four proteins (1472.78 Da, 2936.49 Da, 6556.81 Da and 7081.17 Da) between gastric cancer patients and healthy subjects.
conclusionThe finger print mass spectrum of saliva protein in patients with gastric cancer can be established using gastric cancer proteomics. A diagnostic model for distinguishing protein expression mass spectra of gastric cancer from non-gastric-cancer saliva can be established according to the different expression of proteins 1472.78 Da, 2936.49 Da, 6556.81 Da and 7081.17 Da. The method for early diagnosis of gastric cancer is of certain value for screening special biological markers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.