ArticleGenome research2009
Atypical relaxation of structural constraints in Hox gene clusters of the green anole lizard.
Article in Genome research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 57 citations in OpenAlex.
- The first de novo genome assembly and annotation of a green-blooded skink (Prasinohaema aff. flavipes) from a historic museum sample.The Journal of heredity · 2025Article
- CTCF-dependent insulation ofProceedings of the National Academy of Sciences of the United States of America · 2024Article
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- Genomic Characterization ofAnimals : an open access journal from MDPI · 2022Article
- First Genome of Rock LizardGenes · 2022Article
- Transposable element-derived sequences in vertebrate development.Mobile DNA · 2021Review
- Comparative analysis of squamate brains unveils multi-level variation in cerebellar architecture associated with locomotor specialization.Nature communications · 2019Article
- Evolutionary lability inEvolution letters · 2019Article
- The ecological origins of snakes as revealed by skull evolution.Nature communications · 2018Article
- Accumulation of transposable elements in Hox gene clusters during adaptive radiation of Anolis lizards.Proceedings. Biological sciences · 2016Article
- Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan.eLife · 2016Article
- Tandem amino acid repeats in the green anole (Anolis carolinensis) and other squamates may have a role in increasing genetic variability.BMC genomics · 2016Article
- Hox cluster characterization of Banna caecilian (Ichthyophis bannanicus) provides hints for slow evolution of its genome.BMC genomics · 2015Article
- Restriction and recruitment-gene duplication and the origin and evolution of snake venom toxins.Genome biology and evolution · 2014Article
- Evolution of Hox gene clusters in deuterostomes.BMC developmental biology · 2013Review
- Salamander Hox clusters contain repetitive DNA and expanded non-coding regions: a typical Hox structure for non-mammalian tetrapod vertebrates?Human genomics · 2013Article
- Lizards and LINEs: selection and demography affect the fate of L1 retrotransposons in the genome of the green anole (Anolis carolinensis).Genome biology and evolution · 2013Article
- Evolutionary rate of human tissue-specific genes are related with transposable element insertions.Genetica · 2012Article
- Article
- From lizard to snake; behind the evolution of an extreme body plan.Current genomics · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hox genes control many aspects of embryonic development in metazoans. Previous analyses of this gene family revealed a surprising diversity in terms of gene number and organization between various animal species. In vertebrates, Hox genes are grouped into tightly organized clusters, claimed to be devoid of repetitive sequences. Here, we report the genomic organization of the four Hox loci present in the green anole lizard and show that they have massively accumulated retrotransposons, leading to gene clusters larger in size when compared to other vertebrates. In addition, similar repeats are present in many other development-related gene-containing regions, also thought to be refractory to such repetitive elements. Transposable elements are major sources of genetic variations, including alterations of gene expression, and hence this situation, so far unique among vertebrates, may have been associated with the evolution of the spectacular realm of morphological variations in the body plans of Squamata. Finally, sequence alignments highlight some divergent evolution in highly conserved DNA regions between vertebrate Hox clusters, which may coincide with the emergence of mammalian-specific features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.