Evidence map›Paper›PMID 19228486›Full record

ReviewCurrent atherosclerosis reports2009

The role of C-reactive protein polymorphisms in inflammation and cardiovascular risk.

Fadi G Hage, Alexander J Szalai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Possible Practical Implication of High CRP Levels in PCOS.Clinical medicine insights. Reproductive health · 2019
    Article
  5. Article
  6. Review
  7. C-reactive protein and hypertension.Journal of human hypertension · 2014
    Review
  8. Article
  9. Review
  10. Article
  11. The CRP 1846T/T genotype is associated with a poor prognosis in patients with non-small cell lung cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2010
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fadi G HageDepartment of Medicine, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294, USA. fadihage@uab.edu
Alexander J Szalai
University of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interest in C-reactive protein (CRP) and the association of its serum level in apparently healthy individuals to their cardiovascular disease risk has soared over the past decade. Recent studies have shown that the interindividual variations in CRP levels not only reflect environmental cues but are also a consequence of the genetic variation in the CRP gene itself. The importance of the relationship of CRP gene variants to CRP serum level and cardiovascular disease risk is important to establish CRP gene profiling as a clinical risk prediction tool and also to help test the cause-effect relationship between CRP and vascular disease. This article reviews recent studies that address the relationship of CRP gene polymorphisms to inflammation and cardiovascular risk.

Indexed as

Cardiovascular DiseasesC-Reactive ProteinGenetic Predisposition to DiseaseHumansInflammationPolymorphism, GeneticC-Reactive Protein

Identifiers

PMID19228486
OpenAlexW2070084582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.