ArticleOrganic letters2009
Erythronolides H and I, new erythromycin congeners from a new halophilic actinomycete Actinopolyspora sp. YIM90600.
Article in Organic letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Bioprospecting of Actinobacterial Diversity and Antibacterial Secondary Metabolites from the Sediments of Four Saline Lakes on the Northern Tibetan Plateau.Microorganisms · 2023Article
- New isofuranonaphthoquinones and isoindolequinones from Streptomyces sp. CB01883.The Journal of antibiotics · 2017Article
- Structure and conformational analysis of spiroketals from 6-O-methyl-9(E)-hydroxyiminoerythronolide A.Beilstein journal of organic chemistry · 2015Article
- Article
- Identification of antifungal natural products via Saccharomyces cerevisiae bioassay: insights into macrotetrolide drug spectrum, potency and mode of action.Medical mycology · 2013Article
- Systematic and biotechnological aspects of halophilic and halotolerant actinomycetes.Extremophiles : life under extreme conditions · 2013Article
- Neaumycin: a new macrolide from Streptomyces sp. NEAU-x211.Organic letters · 2012Article
- Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600.Journal of natural products · 2011Article
- Bafilomycins produced by an endophytic actinomycete Streptomyces sp. YIM56209.The Journal of antibiotics · 2011Article
- Cycloheximide and congeners as inhibitors of eukaryotic protein synthesis from endophytic actinomycetes Streptomyces sps. YIM56132 and YIM56141.The Journal of antibiotics · 2011Article
- Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis.Journal of natural products · 2010Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Erythronolides H and I, novel congeners of the clinically important antibacterial drug erythromycin A, have been isolated from the new halophilic actinomycete Actinopolyspora sp. YIM90600. In addition to producing the new erythromycin congeners, A. sp. YIM90600 produces erythromycin C in a high titer. The presence of the C-14 hydroxyl moiety and the C-6/C-18-epoxide in erythronolide H and the spiroketal moiety of erythronolide I sheds new insights into structural diversity of erythromycin analog libraries potentially accessible by combinatorial biosynthesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.