Evidence map›Paper›PMID 19227986›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2009

Electrically addressable vesicles: tools for dielectrophoresis metrology.

Salil P Desai, Michael D Vahey, Joel Voldman

Open access · greenAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 0 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Salil P DesaiDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Michael D Vahey
Joel Voldman
Massachusetts Institute of Technology · US

Funding

A microscale sorting cytometer for cell-based screensR01RR019652 · NCRR · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI VOLDMAN, JOEL · 2004 to 2008
$889k
Continuous cell screening using iso-dielectric separationR21EB005753 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI VOLDMAN, JOEL · 2005 to 2006
$285k
NCRR NIH HHS R01 RR019652NCRR NIH HHS RR199652NIBIB NIH HHS EB005753NIBIB NIH HHS R21 EB005753
6 · The paper itself

Abstract

Dielectrophoresis (DEP) has emerged as an important tool for the manipulation of bioparticles ranging from the submicron to the tens of microns in size. Here we show the use of phospholipid vesicle electroformation techniques to develop a new class of test particles with specifically engineered electrical propserties to enable identifiable dielectrophoretic responses in microfabricated systems. These electrically addressable vesicles (EAVs) enable the creation of electrically distinct populations of test particles for DEP. EAVs offer control of both their inner aqueous core and outer membrane properties; by encapsulating solutions of different electrolyte strength inside the vesicle and by incorporating functionalized phospholipids containing poly(ethylene glycol) (PEG) brushes attached to their hydrophilic headgroup in the vesicle membrane, we demonstrate control of the vesicles' electrical polarizabilities. This combined with the ability to encode information about the properties of the vesicle in its fluorescence signature forms the first steps toward the development of EAV populations as metrology tools for any DEP-based microsystem.

Indexed as

Biocompatible MaterialsElectrochemistryElectrodesElectrophoresis, MicrochipImage Processing, Computer-AssistedMicroscopyMicroscopy, FluorescenceParticle SizePhospholipidsPolyethylene GlycolsPolymersSolutionsSpectrometry, FluorescenceSurface PropertiesBiocompatible MaterialsPhospholipidsPolyethylene GlycolsPolymersSolutions

Identifiers

PMID19227986
PMCPMC2654608
OpenAlexW2226622204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.