Evidence map›Paper›PMID 19226436›Full record

ReviewGenome biology2009

Identifying protein-coding genes in genomic sequences.

Jennifer Harrow, Alinda Nagy, Alexandre Reymond, Tyler Alioto, Laszlo Patthy, Stylianos E Antonarakis, Roderic Guigó

Abstract readReview
In one paragraph

Review in Genome biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jennifer HarrowWellcome Trust Sanger Institute, Wellcome Trust Campus, Hinxton, Cambridge, UK.
Alinda Nagy
Alexandre Reymond
Tyler Alioto
Laszlo Patthy
Stylianos E Antonarakis
Roderic Guigó

Funding

Integrated human genome annotation: generation of a reference gene setU54HG004555 · NHGRI · SANGER INSTITUTE · PI HUBBARD, TIMOTHY JOHN · 2007 to 2012
$11.2M
Mapping Sites of Transcription and RegulationU01HG003147 · NHGRI · AFFYMETRIX, INC. · PI GINGERAS, THOMAS RAYMOND · 2003 to 2006
$4.1M
The Encyclopedia of Genes and Gene VariantsU01HG003150 · NHGRI · MUNICIPAL INSTITUTE OF MEDICAL RESEARCH · PI GUIGO, RODERIC · 2003 to 2006
$2.1M
NHGRI NIH HHS U01 HG003147NHGRI NIH HHS U01 HG003150NHGRI NIH HHS U54 HG004555Wellcome Trust 077198
6 · The paper itself

Abstract

The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets.

Indexed as

AnimalsBase SequenceComputational BiologyGenesGenomeHumansProteinsProteins

Identifiers

PMID19226436
PMCPMC2687780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.