Evidence map›Paper›PMID 19224368›Full record

ArticleAnnals of biomedical engineering2009

High-resolution mapping of in vivo gastrointestinal slow wave activity using flexible printed circuit board electrodes: methodology and validation.

Peng Du, G O'Grady, J U Egbuji, W J Lammers, D Budgett, P Nielsen, J A Windsor, A J Pullan, L K Cheng

Abstract read
In one paragraph

Article in Annals of biomedical engineering, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Electromechanical coupling across the gastroduodenal junction.Acta physiologica (Oxford, England) · 2025
    Review
  7. Simultaneous optical imaging of gastric slow waves and contractions in the in vivo porcine stomach.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  8. [A New Paradigm in Diagnosing Functional Gastroduodenal Disorders: High-Resolution Electrogastrography].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. A Study on Ultrasonic Wireless Power Transfer With Phased Array for Biomedical Implants.IEEE transactions on biomedical circuits and systems · 2023
    Article
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  14. Article
  15. Article
  16. Article
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  18. Article
  19. Review
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng DuBioengineering Institute, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. peng.du@auckland.ac.nz
G O'Grady
J U Egbuji
W J Lammers
D Budgett
P Nielsen
J A Windsor
A J Pullan
L K Cheng

Funding

Realistic models of gastrointestinal bioelectromagnetismR01DK064775 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHENG, LEO · 2004 to 2014
$2.6M
NIDDK NIH HHS R01 DK064775NIDDK NIH HHS R01 DK64775
6 · The paper itself

Abstract

High-resolution, multi-electrode mapping is providing valuable new insights into the origin, propagation, and abnormalities of gastrointestinal (GI) slow wave activity. Construction of high-resolution mapping arrays has previously been a costly and time-consuming endeavor, and existing arrays are not well suited for human research as they cannot be reliably and repeatedly sterilized. The design and fabrication of a new flexible printed circuit board (PCB) multi-electrode array that is suitable for GI mapping is presented, together with its in vivo validation in a porcine model. A modified methodology for characterizing slow waves and forming spatiotemporal activation maps showing slow waves propagation is also demonstrated. The validation study found that flexible PCB electrode arrays are able to reliably record gastric slow wave activity with signal quality near that achieved by traditional epoxy resin-embedded silver electrode arrays. Flexible PCB electrode arrays provide a clinically viable alternative to previously published devices for the high-resolution mapping of GI slow wave activity. PCBs may be mass-produced at low cost, and are easily sterilized and potentially disposable, making them ideally suited to intra-operative human use.

Indexed as

ElectrodesAnimalsBiocompatible MaterialsCopperElectronics, MedicalElectrophysiologyFemaleGastrointestinal TractGoldMotor ActivityMuscle, SmoothReproducibility of ResultsSignal Processing, Computer-AssistedStomachSus scrofaBiocompatible MaterialsCopperGold

Identifiers

PMID19224368
PMCPMC4090363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.