ArticleAnnals of biomedical engineering2009
Characterization of anisotropic diffusion tensor of solute in tissue by video-FRAP imaging technique.
Article in Annals of biomedical engineering, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Human mesenchymal stem/stromal cell-derived extracellular vesicle transport in meniscus fibrocartilage.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Effect of cigarette smoke exposure and cessation on regional diffusion properties in rat intervertebral discs.JOR spine · 2024Article
- Viable Vitreous Grafts of Whole Porcine Menisci for Transplant in the Knee and Temporomandibular Joints.Advanced healthcare materials · 2024Article
- Assessing the role of surface layer and molecular probe size in diffusion within meniscus tissue.PloS one · 2024Article
- Strain-Dependent Diffusivity of Small and Large Molecules in Meniscus.Journal of biomechanical engineering · 2022Article
- High Resolution Micro-Computed Tomography Reveals a Network of Collagen Channels in the Body Region of the Knee Meniscus.Annals of biomedical engineering · 2021Article
- A noninvasive fluorescence imaging-based platform measures 3D anisotropic extracellular diffusion.Nature communications · 2021Article
- EFFECTS OF SOLUTE SIZE AND TISSUE COMPOSITION ON MOLECULAR AND MACROMOLECULAR DIFFUSIVITY IN HUMAN KNEE CARTILAGE.Osteoarthritis and cartilage open · 2020Article
- Molecular and macromolecular diffusion in human meniscus: relationships with tissue structure and composition.Osteoarthritis and cartilage · 2020Article
- Measurement of three-dimensional anisotropic diffusion by multiphoton fluorescence recovery after photobleaching.Annals of biomedical engineering · 2014Article
- Relationship between anisotropic diffusion properties and tissue morphology in porcine TMJ disc.Osteoarthritis and cartilage · 2013Article
- Strain tunes proteolytic degradation and diffusive transport in fibrin networks.Biomacromolecules · 2012Article
- Simultaneous measurement of anisotropic solute diffusivity and binding reaction rates in biological tissues by FRAP.Annals of biomedical engineering · 2011Article
- Anisotropic solute diffusion tensor in porcine TMJ discs measured by FRAP with spatial Fourier analysis.Annals of biomedical engineering · 2010Article
- Relationship between solute transport properties and tissue morphology in human annulus fibrosus.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2009Article
- Characterization of the Concentration-Dependence of Solute Diffusivity and Partitioning in a Model Dextran-Agarose Transport System.Cellular and molecular bioengineering · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
In this study, a new method for determination of an anisotropic diffusion tensor by a single fluorescence recovery after photobleaching (FRAP) experiment was developed. The method was based on two independent analyses of video-FRAP images: the fast Fourier transform and the Karhunen-Loève transform. Computer-simulated FRAP tests were used to evaluate the sensitivity of the method to experimental parameters, such as the initial size of the bleached spot, the choice of the frequencies used in the Fourier analysis, the orientation of the diffusion tensor, and experimental noise. The new method was also experimentally validated by determining the anisotropic diffusion tensor of fluorescein (332 Da) in bovine annulus fibrosus. The results obtained were in agreement with those reported in a previous study. Finally, the method was used to characterize fluorescein diffusion in bovine meniscus. Our findings indicate that fluorescein diffusion in bovine meniscus is anisotropic. This study provides a new tool for the determination of anisotropic diffusion tensor that could be used to investigate the correlation between the structure of biological tissues and their transport properties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.