Trial reportJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2009
Enteral nutrition and biliopancreatic diversion effectively minimize impacts of gastroparesis after pancreaticoduodenectomy.
Trial report in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Postoperative nutritional support after pancreaticoduodenectomy in adults.The Cochrane database of systematic reviews · 2025Pooled it
- Early enteral nutrition after pancreatoduodenectomy: a meta-analysis of randomized controlled trials.Langenbeck's archives of surgery · 2013Pooled it
- A systematic review of methodology in nutritional trials in patients undergoing pancreatoduodenectomy.Hepatobiliary surgery and nutrition · 2026Review
- Impact of Intravenous Fluids and Enteral Nutrition on the Severity of Gastrointestinal Dysfunction: A Systematic Review and Meta-analysis.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020Article
- Current evidence of nutritional therapy in pancreatoduodenectomy: Systematic review of randomized controlled trials.Annals of gastroenterological surgery · 2019Review
- Does the Ileal Brake Contribute to Delayed Gastric Emptying After Pancreatoduodenectomy?Digestive diseases and sciences · 2017Review
- Pancreatic Fistula and Delayed Gastric Emptying After Pancreatectomy: Where do We Stand?The Indian journal of surgery · 2015Article
- Review
- Reflux esophagitis and marginal ulcer after pancreaticoduodenectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince gastroparesis is unavoidable in a certain proportion of patients after pancreaticoduodenectomy, measures to avoid its occurrence or at least minimize its impact are needed. A prospective randomized trial was performed to test the effectiveness of biliopancreatic diversion with modified Roux-en-Y gastrojejunostomy reconstruction and of enteral feeding to minimize impacts of gastroparesis after pancreaticoduodenectomy.
methodsIn total, 247 patients with periampullary tumors were randomized at the time of pancreaticoduodenectomy to have either (1) modified Roux-en-Y gastrojejunostomy reconstruction (by creating a side-to-side jejunojejunostomy between afferent and efferent loop and closing the afferent loop with a TA-30-3.5 stapler) and insertion of a jejunostomy feeding tube (modified group) or (2) conventional gastric bypass (control group). Outcomes including complications, duration of nasogastric tube placement, and length of hospital stay were followed prospectively.
resultsGastroparesis occurred in 20 patients (16.3%) in the modified group and 27 patients in the control group (21.7%, P = 0.27). However, the International Study Group of Pancreatic Surgery grades of gastroparesis were significantly lower in the modified group (10A, 5B, 5C) than in the control group (4A, 5B, 18C, P = 0.01).
conclusionsModified procedure does not reduce the risk of gastroparesis but appears to reduce the severity when it occurs.
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Registered trials
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