ArticleAntimicrobial agents and chemotherapy2009
Effects of double and triple combinations of antifungal drugs in a murine model of disseminated infection by Scedosporium prolificans.
Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
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- SystemicInfection and drug resistance · 2024Article
- Activity of Amphotericin B Formulations and Voriconazole, Alone or in Combination, against Biofilms ofAntimicrobial agents and chemotherapy · 2021Article
- Fungus-Specific CD4 T Cells as Specific Sensors for Identification of Pulmonary Fungal Infections.Mycopathologia · 2018Review
- Progress in Definition, Prevention and Treatment of Fungal Infections in Cystic Fibrosis.Mycopathologia · 2018Review
- Fatal breakthrough mucormycosis in a multivisceral transplant patient receiving micafungin: Case report and literature review.IDCases · 2018Article
- Article
- Experimental therapy with azoles against Candida guilliermondii.Antimicrobial agents and chemotherapy · 2014Article
- Impact of multidrug-resistant organisms on patients considered for lung transplantation.Infectious disease clinics of North America · 2013Review
- Emerging fungal infections in solid organ transplant recipients.Infectious disease clinics of North America · 2013Review
- MIC values of voriconazole are predictive of treatment results in murine infections by Aspergillus terreus species complex.Antimicrobial agents and chemotherapy · 2013Article
- Evaluation of the in vitro activity of voriconazole as predictive of in vivo outcome in a murine Aspergillus fumigatus infection model.Antimicrobial agents and chemotherapy · 2013Article
- Species-specific antifungal susceptibility patterns of Scedosporium and Pseudallescheria species.Antimicrobial agents and chemotherapy · 2012Article
- Multiple Scedosporium apiospermum abscesses in a woman survivor of a tsunami in northeastern Japan: a case report.Journal of medical case reports · 2011Article
- In vitro activity and in vivo efficacy of posaconazole in treatment of murine infections by different isolates of the Aspergillus terreus complex.Antimicrobial agents and chemotherapy · 2011Article
- Melanized fungi in human disease.Clinical microbiology reviews · 2010Review
- Correlation of in vitro activity, serum levels, and in vivo efficacy of posaconazole against Rhizopus microsporus in a murine disseminated infection.Antimicrobial agents and chemotherapy · 2009Article
- Efficacy of triazoles in a murine disseminated infection by Candida krusei.Antimicrobial agents and chemotherapy · 2009Article
- Successful Treatment ofAllergy & rhinology (Providence, R.I.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have evaluated the efficacies of micafungin, amphotericin B, and voriconazole, alone and in double and triple combinations, in a murine model of systemic infection by Scedosporium prolificans. Micafungin combined with voriconazole or amphotericin B was the most effective, these being the only treatments able to prolong survival and to reduce the fungal load in the kidneys and brain. Triple combinations of these drugs did not improve the results obtained with double combinations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.