ArticleDiabetes care2009
Insufficient control of blood pressure and incident diabetes.
Article in Diabetes care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery.Reviews in cardiovascular medicine · 2025Pooled it
- Degree of Blood Pressure Control and Incident Diabetes Mellitus in Chinese Adults With Hypertension.Journal of the American Heart Association · 2020Trial
- Development and multi-cohort validation of a clinical score for predicting type 2 diabetes mellitus.PloS one · 2019Trial
- Should thiazide diuretics be given as first line antihypertensive therapy or in addition to other medications?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015Trial
- Antihypertensive response to combination of olmesartan and amlodipine does not depend on method and time of drug administration.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Trial
- Nut consumption and risk of type II diabetes in the Physicians' Health Study.European journal of clinical nutrition · 2010Trial
- A machine learning approach for type 2 diabetes diagnosis and prognosis using tailored heterogeneous feature subsets.Medical & biological engineering & computing · 2025Article
- Statin-induced risk of diabetes does not reduce cardiovascular benefits in primary prevention: a 6-year propensity-score matched study in a large population.Cardiovascular diabetology · 2025Article
- Classification and identification of risk factors for type 2 diabetes.World journal of diabetes · 2025Review
- Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.Frontiers in endocrinology · 2025Article
- Risk Factors and Predictive Model for Stress Hyperglycemia After Cardiac Surgery in Non-Diabetic Patients.Journal of multidisciplinary healthcare · 2025Article
- Metabolic dysfunction-associated steatotic liver disease: A superior predictor for incident type 2 diabetes over traditional criteria - NAGALA study.Journal of diabetes investigation · 2024Article
- Correlates of diabetes mellitus and hypertension in India: Change as evidenced from NFHS- 4 and 5 during 2015-2021.PloS one · 2024Article
- A multi-omics approach to investigate characteristics of gut microbiota and metabolites in hypertension and diabetic nephropathy SPF rat models.Frontiers in microbiology · 2024Article
- Kidney Tubular IL-1β ENaCtivation in Diabetes and Salt-Sensitive Hypertension.Circulation research · 2022Article
- Hypertension and Type 2 Diabetes-The Novel Treatment Possibilities.International journal of molecular sciences · 2022Review
- Article
- Determinants of improvement of left ventricular mechano-energetic efficiency in hypertensive patients.Frontiers in cardiovascular medicine · 2022Article
- Association of hypertension and incident diabetes in Chinese adults: a retrospective cohort study using propensity-score matching.BMC endocrine disorders · 2021Article
- The Risk of Type 2 Diabetes Mellitus in a Russian Population Cohort According to Data from the HAPIEE Project.Journal of personalized medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIncidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control. We evaluated the hazard of diabetes in relation to blood pressure control in treated hypertensive patients. RESEARCH DESIGN AND
methodsNondiabetic, otherwise healthy, hypertensive patients (N = 1,754, mean +/- SD age 52 +/- 11 years, 43% women) participated in a network over 3.4 +/- 1 years of follow-up. Blood pressure was considered uncontrolled if systolic was >or=140 mmHg and/or diastolic was >or=90 mmHg at the last outpatient visit. Diabetes was defined according to American Diabetes Association guidelines.
resultsUncontrolled blood pressure despite antihypertensive treatment was found in 712 patients (41%). At baseline, patients with uncontrolled blood pressure were slightly younger than patients with controlled blood pressure (51 +/- 11 vs. 53 +/- 12 years, P < 0.001), with no differences in sex distribution, BMI, duration of hypertension, baseline blood pressure, fasting glucose, serum creatinine and potassium, lipid profile, or prevalence of metabolic syndrome. During follow-up, 109 subjects developed diabetes. Incidence of diabetes was significantly higher in patients with uncontrolled (8%) than in those with controlled blood pressure (4%, odds ratio 2.08, P < 0.0001). In Cox regression analysis controlling for baseline systolic blood pressure and BMI, family history of diabetes, and physical activity, uncontrolled blood pressure doubled the risk of incident diabetes (hazard ratio [HR] 2.10, P < 0.001), independently of significant effects of age (HR 1.02 per year, P = 0.03) and baseline fasting glucose (HR 1.10 per mg/dl, P < 0.001).
conclusionsIn a large sample of treated nondiabetic hypertensive subjects, uncontrolled blood pressure is associated with twofold increased risk of incident diabetes independently of age, BMI, baseline blood pressure, or fasting glucose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.