ReviewAnalytical and bioanalytical chemistry2009
Label-free technologies for quantitative multiparameter biological analysis.
Review in Analytical and bioanalytical chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Progress in silicon-based reconfigurable and programmable all-optical signal processing chips.Frontiers of optoelectronics · 2025Review
- Review
- Computational approaches in rheumatic diseases - Deciphering complex spatio-temporal cell interactions.Computational and structural biotechnology journal · 2023Review
- Enhanced Label-Free Nanoplasmonic Cytokine Detection in SARS-CoV-2 Induced Inflammation Using Rationally Designed Peptide Aptamer.ACS applied materials & interfaces · 2022Article
- Demonstration of Ultra-High-Q Silicon Microring Resonators for Nonlinear Integrated Photonics.Micromachines · 2022Article
- Disease-Relevant Single Cell Photonic Signatures Identify S100β Stem Cells and their Myogenic Progeny in Vascular Lesions.Stem cell reviews and reports · 2021Article
- Experimental study of an evanescent-field biosensor based on 1D photonic bandgap structures.Beilstein journal of nanotechnology · 2019Article
- Multiplexed silicon photonic sensor arrays enable facile characterization of coagulation protein binding to nanodiscs with variable lipid content.The Journal of biological chemistry · 2017Article
- Label-free cytokine micro- and nano-biosensing towards personalized medicine of systemic inflammatory disorders.Advanced drug delivery reviews · 2015Review
- Bioanalytical chemistry of cytokines--a review.Analytica chimica acta · 2015Review
- Advances in plasmonic technologies for point of care applications.Chemical reviews · 2014Review
- Ultraspecific and highly sensitive nucleic acid detection by integrating a DNA catalytic network with a label-free microcavity.Small (Weinheim an der Bergstrasse, Germany) · 2014Article
- A mathematical method for extracting cell secretion rate from affinity biosensors continuously monitoring cell activity.Biomicrofluidics · 2014Review
- Multispot, label-free biodetection at a phantom plastic-water interface.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Zwitterionic polymer-modified silicon microring resonators for label-free biosensing in undiluted human plasma.Biosensors & bioelectronics · 2013Article
- Protein immobilization techniques for microfluidic assays.Biomicrofluidics · 2013Review
- Label-free detection with high-Q microcavities: a review of biosensing mechanisms for integrated devices.Nanophotonics (Berlin, Germany) · 2012Article
- Attaching biological probes to silica optical biosensors using silane coupling agents.Journal of visualized experiments : JoVE · 2012Article
- Antibody colocalization microarray: a scalable technology for multiplex protein analysis in complex samples.Molecular & cellular proteomics : MCP · 2012Article
- High-Q optical sensors for chemical and biological analysis.Analytical chemistry · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In the postgenomic era, information is king and information-rich technologies are critically important drivers in both fundamental biology and medicine. It is now known that single-parameter measurements provide only limited detail and that quantitation of multiple biomolecular signatures can more fully illuminate complex biological function. Label-free technologies have recently attracted significant interest for sensitive and quantitative multiparameter analysis of biological systems. There are several different classes of label-free sensors that are currently being developed both in academia and in industry. In this critical review, we highlight, compare, and contrast some of the more promising approaches. We describe the fundamental principles of these different methods and discuss advantages and disadvantages that might potentially help one in selecting the appropriate technology for a given bioanalytical application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.